Immunomodulatory effect of phytoactive compounds on human health: a narrative review integrated with bioinformatics approach
S Choudhary, S Khan, S Rustagi… - Current Topics in …, 2024 - ingentaconnect.com
Background: Immunomodulation is the modification of immune responses to control disease
progression. While the synthetic immunomodulators have proven efficacy, they are coupled …
progression. While the synthetic immunomodulators have proven efficacy, they are coupled …
Dietary aflatoxin B1 and antimalarial—a lumefantrine/artesunate—therapy perturbs male rat reproductive function via pro-inflammatory and oxidative mechanisms
We investigated the impact of Coartem™(COA) and aflatoxin B1 (AFB1) on rats'
hypothalamus, epididymis, and testis. Male rats were randomly grouped (n= 5 rats) and …
hypothalamus, epididymis, and testis. Male rats were randomly grouped (n= 5 rats) and …
Antioxidant, anti-inflammatory, and anti-apoptotic effects of genkwanin against aflatoxin B1-induced testicular toxicity
MU Ijaz, A Ishtiaq, A Tahir, MA Alvi, A Rafique… - Toxicology and Applied …, 2023 - Elsevier
Abstract Aflatoxin B 1 (AFB 1) is the most hazardous aflatoxin that causes significant
damage to the male reproductive system. Genkwanin (GNK) is a bioactive flavonoid that …
damage to the male reproductive system. Genkwanin (GNK) is a bioactive flavonoid that …
Natural compounds mitigate mycotoxins-induced neurotoxicity by modulating oxidative tonus: in vitro and in vivo insights – a review
L Del Fabbro, MHM Sari, LM Ferreira… - Food Additives & …, 2024 - Taylor & Francis
This review explores the repercussions of mycotoxin contamination in food and feed,
emphasising potential threats to agriculture, animal husbandry and public health. The …
emphasising potential threats to agriculture, animal husbandry and public health. The …
[HTML][HTML] Effect of zearalenone on aflatoxin B1-induced intestinal and ovarian toxicity in pregnant and lactating rats
K Wu, M Liu, H Wang, SA Rajput, OM Al Zoubi… - Ecotoxicology and …, 2023 - Elsevier
Abstract Aflatoxin B1 (AFB1) and zearalenone (ZEN) cause serious damage to mammals,
but few studies have investigated the impacts of these toxins on pregnant and lactating …
but few studies have investigated the impacts of these toxins on pregnant and lactating …
Epirubicin toxicity in rat's ovary and uterus: A protective role of 3-Indolepropionic acid supplementation
SE Owumi, GE Adebisi, OA Odunola - Chemico-Biological Interactions, 2023 - Elsevier
Abstract The “anthracycline, Epirubicin (EPI),” in managing breast cancer, is highly cytotoxic.
Tryptophan-derived 3-indolepropionic acid (3-IPA) decreases oxidative damage, and its …
Tryptophan-derived 3-indolepropionic acid (3-IPA) decreases oxidative damage, and its …
Co-exposure to aflatoxin B1 and therapeutic coartem worsens hepatic and renal function through enhanced oxido-inflammatory responses and apoptosis in rats
Abstract Aflatoxin B1 (AFB 1) is a mycotoxin synthesised as a secondary metabolite by
members of the Aspergillus species contaminating agricultural produce. Aspergillus species …
members of the Aspergillus species contaminating agricultural produce. Aspergillus species …
Accidental lead in contaminated pipe-borne water and dietary furan intake perturbs rats' hepatorenal function altering oxidative, inflammatory, and apoptotic balance
Inadvertent exposure to furan and Pb is associated with hepatorenal abnormalities in
humans and animals. It is perceived that these two chemical species may work in synergy to …
humans and animals. It is perceived that these two chemical species may work in synergy to …
Aflatoxin B1-induced dysfunction in male rats' reproductive indices were abated by Sorghum bicolor (L. Moench) hydrophobic fraction
The burden of infertility distresses millions of families worldwide. The harmful effects of
aflatoxin B1 (AFB1) on the reproductive system involve oxidative stress, culminating in …
aflatoxin B1 (AFB1) on the reproductive system involve oxidative stress, culminating in …
Protective effect of selenomethionine on rabbit testicular injury induced by Aflatoxin B1
Z Zhang, Z Zhang, S Liu, S Wei, L Wei, X Zhu… - Science of The Total …, 2024 - Elsevier
The aim of this study was to investigate the alleviating effect of selenomethionine (SeMet) on
aflatoxin B1 (AFB1)-induced testicular injury in rabbits. Twenty-five 90-d-old rabbits were …
aflatoxin B1 (AFB1)-induced testicular injury in rabbits. Twenty-five 90-d-old rabbits were …