Emerging trends in the field of inflammation and proteinopathy in ALS/FTD spectrum disorder
F De Marchi, T Franjkic, P Schito, T Russo, J Nimac… - Biomedicines, 2023 - mdpi.com
Proteinopathy and neuroinflammation are two main hallmarks of neurodegenerative
diseases. They also represent rare common events in an exceptionally broad landscape of …
diseases. They also represent rare common events in an exceptionally broad landscape of …
[HTML][HTML] Pathological mechanisms of amyotrophic lateral sclerosis
Y Hu, W Chen, C Wei, S Jiang, S Li… - Neural Regeneration …, 2024 - journals.lww.com
Amyotrophic lateral sclerosis refers to a neurodegenerative disease involving the motor
system, the cause of which remains unexplained despite several years of research. Thus …
system, the cause of which remains unexplained despite several years of research. Thus …
Novel gene–intergenic fusion involving ubiquitin E3 ligase UBE3C causes distal hereditary motor neuropathy
AN Cutrupi, RK Narayanan, G Perez-Siles, BR Grosz… - Brain, 2023 - academic.oup.com
Distal hereditary motor neuropathies (dHMNs) are a group of inherited diseases involving
the progressive, length-dependent axonal degeneration of the lower motor neurons. There …
the progressive, length-dependent axonal degeneration of the lower motor neurons. There …
Integrating transcriptomic and structural insights: revealing drug repurposing opportunities for sporadic ALS
N Sunildutt, F Ahmed, AR Chethikkattuveli Salih… - ACS …, 2024 - ACS Publications
Amyotrophic lateral sclerosis (ALS) is a progressive and devastating neurodegenerative
disorder characterized by the loss of upper and lower motor neurons, resulting in debilitating …
disorder characterized by the loss of upper and lower motor neurons, resulting in debilitating …
A Diagnostic Gene-Expression Signature in Fibroblasts of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease with
limited treatment options. Diagnosis can be difficult due to the heterogeneity and non …
limited treatment options. Diagnosis can be difficult due to the heterogeneity and non …
[HTML][HTML] Tracing ALS Degeneration: Insights from Spinal Cord and Cortex Transcriptomes
Background/Objectives: Amyotrophic Lateral Sclerosis is a progressive neurodegenerative
disorder characterized by the loss of upper and lower motor neurons. Key factors …
disorder characterized by the loss of upper and lower motor neurons. Key factors …
Systematic Review and Meta-Analyses of Aminopeptidases as Prognostic Biomarkers in Amyotrophic Lateral Sclerosis
B Teruel-Peña, JL Gómez-Urquiza… - International Journal of …, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the progressive loss of motor neurons in the spinal cord, brain stem, and cerebral cortex …
the progressive loss of motor neurons in the spinal cord, brain stem, and cerebral cortex …
肌萎缩性脊髓侧索硬化的致病机制
Y Hu, W Chen, C Wei, S Jiang, S Li, X Wang… - 中国神经再生研究(英文 …, 2024 - sjzsyj.com.cn
肌萎缩脊髓侧索硬化是一种涉及运动系统的神经退行性疾病. 尽管经过多年的研究,
其病因仍未得到确切的解释, 了解和治疗该疾病的道路依然漫长. 就目前的研究表明 …
其病因仍未得到确切的解释, 了解和治疗该疾病的道路依然漫长. 就目前的研究表明 …
Proteomics Analysis of Lymphoblastoid Cell Lines from Patients with Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) consists of the progressive degeneration of motor
neurons, caused by poorly understood mechanisms for which there is no cure. Some of the …
neurons, caused by poorly understood mechanisms for which there is no cure. Some of the …
Novel gene-intergenic fusion involving ubiquitin E3 ligase UBE3C causes distal hereditary motor neuropathy: A new mechanism for motor neuron degeneration
AN Cutrupi, RK Narayanan, G Perez-Siles, BR Grosz… - bioRxiv, 2022 - biorxiv.org
Distal hereditary motor neuropathies (dHMNs) are a group of inherited diseases involving
the progressive, length-dependent axonal degeneration of the lower motor neurons. There …
the progressive, length-dependent axonal degeneration of the lower motor neurons. There …