High‐throughput metabolomics by 1D NMR

A Vignoli, V Ghini, G Meoni, C Licari… - Angewandte Chemie …, 2019 - Wiley Online Library
Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …

Metabolic phenotyping in clinical and surgical environments

JK Nicholson, E Holmes, JM Kinross, AW Darzi… - Nature, 2012 - nature.com
Metabolic phenotyping involves the comprehensive analysis of biological fluids or tissue
samples. This analysis allows biochemical classification of a person's physiological or …

[HTML][HTML] Breast cancer in the era of integrating “Omics” approaches

C Rossi, I Cicalini, MC Cufaro, A Consalvo… - Oncogenesis, 2022 - nature.com
Worldwide, breast cancer is the leading cause of cancer-related deaths in women. Breast
cancer is a heterogeneous disease characterized by different clinical outcomes in terms of …

[HTML][HTML] Identification of metabolic pathways contributing to ER+ breast cancer disparities using a machine-learning pipeline

A Santaliz-Casiano, D Mehta, OC Danciu, H Patel… - Scientific reports, 2023 - nature.com
African American (AA) women in the United States have a 40% higher breast cancer
mortality rate than Non-Hispanic White (NHW) women. The survival disparity is particularly …

Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer

I Bertini, S Cacciatore, BV Jensen, JV Schou… - Cancer research, 2012 - AACR
Earlier detection of patients with metastatic colorectal cancer (mCRC) might improve their
treatment and survival outcomes. In this study, we used proton nuclear magnetic resonance …

[HTML][HTML] Novel personalized pathway-based metabolomics models reveal key metabolic pathways for breast cancer diagnosis

S Huang, N Chong, NE Lewis, W Jia, G Xie… - Genome medicine, 2016 - Springer
Background More accurate diagnostic methods are pressingly needed to diagnose breast
cancer, the most common malignant cancer in women worldwide. Blood-based …

[HTML][HTML] Metabolomics: the stethoscope for the twenty-first century

H Ashrafian, V Sounderajah, R Glen, T Ebbels… - Medical Principles and …, 2021 - karger.com
Metabolomics encompasses the systematic identification and quantification of all metabolic
products in the human body. This field could provide clinicians with novel sets of diagnostic …

Metabolomics in breast cancer: A decade in review

A McCartney, A Vignoli, L Biganzoli, R Love… - Cancer Treatment …, 2018 - Elsevier
Breast cancer (BC) is a heterogeneous disease which has been characterised and stratified
by many platforms such as clinicopathological risk factors, genomic assays, computer …

A serum nuclear magnetic resonance-based metabolomic signature of advanced metastatic human breast cancer

E Jobard, C Pontoizeau, BJ Blaise, T Bachelot… - Cancer letters, 2014 - Elsevier
Breast cancer (BC) displays a high heterogeneity from histology to prognosis, metastatic
evolution and treatment responses. We report here a 1 H NMR-based metabolic …

[HTML][HTML] Metabolomics approach for predicting response to neoadjuvant chemotherapy for breast cancer

S Wei, L Liu, J Zhang, J Bowers, GAN Gowda… - Molecular …, 2013 - Elsevier
Breast cancer is a clinically heterogeneous disease, which necessitates a variety of
treatments and leads to different outcomes. As an example, only some women will benefit …