A comprehensive review of viral characteristics, transmission, pathophysiology, immune response, and management of SARS-CoV-2 and COVID-19 as a basis for …

CR Triggle, D Bansal, H Ding, MM Islam… - Frontiers in …, 2021 - frontiersin.org
COVID-19 emerged from China in December 2019 and during 2020 spread to every
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …

Efficacy and safety of azithromycin in Covid‐19 patients: A systematic review and meta‐analysis of randomized clinical trials

AM Kamel, MSA Monem, NA Sharaf… - Reviews in medical …, 2022 - Wiley Online Library
Azithromycin (AZM) is commonly used in Covid‐19 patients based on low‐quality evidence,
increasing the risk of developing adverse events and antimicrobial resistance. The current …

High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study

L Weaver, A Das, S Saffaran, N Yehya, TE Scott… - Annals of intensive …, 2021 - Springer
Background There is on-going controversy regarding the potential for increased respiratory
effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing …

Potential neurological manifestations of COVID-19: a narrative review

JV Pergolizzi Jr, RB Raffa, G Varrassi… - Postgraduate …, 2022 - Taylor & Francis
Neurological manifestations are increasingly reported in a subset of COVID-19 patients.
Previous infections related to coronaviruses, namely Severe Acute Respiratory Syndrome …

Diagnosis and management of acute respiratory distress syndrome in a time of COVID-19

S Kassirian, R Taneja, S Mehta - Diagnostics, 2020 - mdpi.com
Acute respiratory distress syndrome (ARDS) remains a serious illness with significant
morbidity and mortality, characterized by hypoxemic respiratory failure most commonly due …

Respiratory co-infections: modulators of SARS-CoV-2 patients' clinical sub-phenotype

P Mehta, S Sahni, S Siddiqui, N Mishra… - Frontiers in …, 2021 - frontiersin.org
Co-infection with ancillary pathogens is a significant modulator of morbidity and mortality in
infectious diseases. There have been limited reports of co-infections accompanying SARS …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
caused the greatest pandemic of our century. Many of the deaths related to it are due to a …

[HTML][HTML] An immune-protein score combining TRAIL, IP-10 and CRP for predicting severe COVID-19 disease

NS Mastboim, A Angel, O Shaham, TI Ber, R Navon… - Cytokine, 2023 - Elsevier
COVID-19 patients are oftentimes over-or under-treated due to a deficit in predictive
management tools. This study reports derivation of an algorithm that integrates the host …

Indications for tracheal intubation in patients with coronavirus disease 2019 (COVID-19)

A Pisano, A Yavorovskiy, L Verniero… - … of Cardiothoracic and …, 2020 - pmc.ncbi.nlm.nih.gov
With more than 53 million cases of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection worldwide (at the time of writing) and the recent new increase in contagion …

Reinforcement learning assisted oxygen therapy for COVID-19 patients under intensive care

H Zheng, J Zhu, W Xie, J Zhong - BMC medical informatics and decision …, 2021 - Springer
Abstract Background Patients with severe Coronavirus disease 19 (COVID-19) typically
require supplemental oxygen as an essential treatment. We developed a machine learning …