Alterations in neuronal activity in basal ganglia-thalamocortical circuits in the parkinsonian state

A Galvan, A Devergnas, T Wichmann - Frontiers in neuroanatomy, 2015 - frontiersin.org
In patients with Parkinson's disease and in animal models of this disorder, neurons in the
basal ganglia and related regions in thalamus and cortex show changes that can be …

Motor thalamus integration of cortical, cerebellar and basal ganglia information: implications for normal and parkinsonian conditions

C Bosch-Bouju, BI Hyland… - Frontiers in computational …, 2013 - frontiersin.org
Motor thalamus (Mthal) is implicated in the control of movement because it is strategically
located between motor areas of the cerebral cortex and motor-related subcortical structures …

Oscillatory multiplexing of neural population codes for interval timing and working memory

BM Gu, H van Rijn, WH Meck - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Interval timing and working memory are critical components of cognition that are supported
by neural oscillations in prefrontal–striatal–hippocampal circuits. In this review, the …

Pallidostriatal projections promote β oscillations in a dopamine-depleted biophysical network model

VL Corbit, TC Whalen, KT Zitelli, SY Crilly… - Journal of …, 2016 - Soc Neuroscience
In the basal ganglia, focused rhythmicity is an important feature of network activity at certain
stages of motor processing. In disease, however, the basal ganglia develop amplified …

Long-term dopamine neurochemical monitoring in primates

HN Schwerdt, H Shimazu, K Amemori… - Proceedings of the …, 2017 - National Acad Sciences
Many debilitating neuropsychiatric and neurodegenerative disorders are characterized by
dopamine neurotransmitter dysregulation. Monitoring subsecond dopamine release …

Hypocretin (orexin) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need

A Vassalli, P Franken - … of the National Academy of Sciences, 2017 - National Acad Sciences
Hcrt gene inactivation in mice leads to behavioral state instability, abnormal transitions to
paradoxical sleep, and cataplexy, hallmarks of narcolepsy. Sleep homeostasis is, however …

Oscillatory activity in the cortico‐basal ganglia‐thalamic neural circuits in Parkinson's disease

A Singh - European Journal of Neuroscience, 2018 - Wiley Online Library
Dopamine is an important neurotransmitter that maintains the balance within the basal
ganglia between the direct pathway, which promotes movement, and the indirect pathway …

Npas1+ pallidal neurons target striatal projection neurons

KE Glajch, DA Kelver, DJ Hegeman, Q Cui… - Journal of …, 2016 - Soc Neuroscience
Compelling evidence demonstrates that the external globus pallidus (GPe) plays a key role
in processing sensorimotor information. An anatomical projection from the GPe to the dorsal …

Place vs. response learning: history, controversy, and neurobiology

J Goodman - Frontiers in Behavioral Neuroscience, 2021 - frontiersin.org
The present article provides a historical review of the place and response learning plus-
maze tasks with a focus on the behavioral and neurobiological findings. The article begins …

Impaired dual tasking in Parkinson's disease is associated with reduced focusing of cortico-striatal activity

F Nieuwhof, BR Bloem, MF Reelick, E Aarts, I Maidan… - Brain, 2017 - academic.oup.com
See Bell et al.(doi: 10.1093/awx063) for a scientific commentary on this article. Impaired dual
tasking, namely the inability to concurrently perform a cognitive and a motor task (eg 'stops …