The protein family of glucose transport facilitators: It's not only about glucose after all
R Augustin - IUBMB life, 2010 - Wiley Online Library
The protein family of facilitative glucose transporters comprises 14 isoforms that share
common structural features such as 12 transmembrane domains, N‐and C‐termini facing …
common structural features such as 12 transmembrane domains, N‐and C‐termini facing …
Mouse models of diabetic nephropathy
Diabetic nephropathy is a major cause of ESRD worldwide. Despite its prevalence, a lack of
reliable animal models that mimic human disease has delayed the identification of specific …
reliable animal models that mimic human disease has delayed the identification of specific …
American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with …
WT Garvey, JI Mechanick, EM Brett, AJ Garber… - Endocrine Practice, 2016 - Elsevier
Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …
Clinical Endocrinologists (AACE) Board of Directors and the American College of …
Pathogenetic mechanisms of diabetic nephropathy
FP Schena, L Gesualdo - Journal of the American society of …, 2005 - journals.lww.com
Diabetes is the leading cause of ESRD because diabetic nephropathy develops in 30 to
40% of patients. Diabetic nephropathy does not develop in the absence of hyperglycemia …
40% of patients. Diabetic nephropathy does not develop in the absence of hyperglycemia …
Nephropathy in patients with type 2 diabetes mellitus
E Ritz, SR Orth - New England Journal of Medicine, 1999 - Mass Medical Soc
In the not-so-distant past, type 2 diabetes mellitus was thought to be a relatively benign
condition, at least in the elderly, with relatively little effect on life expectancy or renal function …
condition, at least in the elderly, with relatively little effect on life expectancy or renal function …
[HTML][HTML] Pathophysiology of the diabetic kidney
V Vallon, R Komers - Comprehensive Physiology, 2011 - ncbi.nlm.nih.gov
Diabetes mellitus contributes greatly to morbidity, mortality, and overall health care costs. In
major part, these outcomes derive from the high incidence of progressive kidney dysfunction …
major part, these outcomes derive from the high incidence of progressive kidney dysfunction …
Pathophysiology and pharmacological treatment of insulin resistance
S Matthaei, M Stumvoll, M Kellerer… - Endocrine …, 2000 - academic.oup.com
Diabetes mellitus type 2 is a world-wide growing health problem affecting more than 150
million people at the beginning of the new millennium. It is believed that this number will …
million people at the beginning of the new millennium. It is believed that this number will …
Genomewide search for type 2 diabetes–susceptibility genes in French Whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27 …
N Vionnet, S Dupont, S Gallina, S Francke… - The American Journal of …, 2000 - cell.com
Despite recent advances in the molecular genetics of type 2 diabetes, the majority of
susceptibility genes in humans remain to be identified. We therefore conducted a 10-cM …
susceptibility genes in humans remain to be identified. We therefore conducted a 10-cM …
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese
To investigate the underlying mechanisms of T2D pathogenesis, we looked for diabetes
susceptibility genes that increase the risk of type 2 diabetes (T2D) in a Han Chinese …
susceptibility genes that increase the risk of type 2 diabetes (T2D) in a Han Chinese …
Candidate gene association study in type 2 diabetes indicates a role for genes involved in β-cell function as well as insulin action
I Barroso, J Luan, RPS Middelberg, AH Harding… - PLoS …, 2003 - journals.plos.org
Type 2 diabetes is an increasingly common, serious metabolic disorder with a substantial
inherited component. It is characterised by defects in both insulin secretion and action …
inherited component. It is characterised by defects in both insulin secretion and action …