The pancreatic islet β cell senses circulating levels of calorigenic nutrients to secrete insulin
according to the needs of the organism. Altered insulin secretion is linked to various …

The metabolic syndrome (MetS) is comprised of a cluster of closely related risk factors,
including visceral adiposity, insulin resistance, hypertension, high triglyceride, and low high …

Extensively revised, the fourth edition of this highly successful book takes into account the
many newly determined protein structures that provide molecular insight into chemiosmotic …

The aim of this study was to investigate the effects of excessive copper (Cu)-induced
cytotoxicity on oxidative stress and mitochondrial apoptosis in chicken hepatocytes. Chicken …

Abstract Purpose of Review This review summarizes the alterations in the β-cell observed in
type 2 diabetes (T2D), focusing on changes in β-cell identity and mass and changes …

This review focuses on the human pancreatic islet—including its structure, cell composition,
development, function, and dysfunction. After providing a historical timeline of key …

Introduction: Obesity and type 2 diabetes are growing health problems worldwide. The three
principal diabetogenic factors are adiposity, insulin resistance in skeletal muscle, and …

Background: Diabetes is one of the most challenging health problems in 21st century. It is a
group of endocrine-metabolic disorder characterized by high glucose level (hyperglycemia) …

Pancreatic β cell dysfunction, ie, failure to provide insulin in concentrations sufficient to
control blood sugar, is central to the etiology of all types of diabetes. Current evidence …

Patients with type 2 diabetes (T2D) are known to have mitochondrial dysfunction and
increased insulin resistance (IR), but the underlying mechanisms are not well understood …