Mechanisms involved in the side effects of glucocorticoids

H Schäcke, WD Döcke, K Asadullah - Pharmacology & therapeutics, 2002 - Elsevier
Glucocorticoids (GCs) represent the most important and frequently used class of anti-
inflammatory drugs. While the therapeutic effects of GCs have been known and used for …

Prenatal glucocorticoids and long-term programming

JR Seckl - European journal of endocrinology, 2004 - academic.oup.com
Epidemiological evidence suggests that low birth weight is associated with an increased risk
of cardiovascular, metabolic and neuroendocrine disorders in adult life. Glucocorticoid …

Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

V Compernolle, K Brusselmans, T Acker, P Hoet… - Nature medicine, 2002 - nature.com
Respiratory distress syndrome (RDS) due to insufficient production of surfactant is a
common and severe complication of preterm delivery. Here, we report that loss of the …

Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth

FC Brownfoot, DI Gagliardi, E Bain… - Cochrane Database …, 2013 - cochranelibrary.com
Background Despite the widespread use of antenatal corticosteroids to prevent respiratory
distress syndrome in preterm infants, there is currently no consensus as to the type of …

Glucocorticoid programming

JR Seckl, MJ Meaney - Annals of the New York Academy of …, 2004 - Wiley Online Library
Epidemiological evidence suggests that an adverse fetal environment permanently
programs physiology, leading to increased risks of cardiovascular, metabolic, and …

Patterns of motor disability in very preterm children

M Bracewell, N Marlow - Mental retardation and developmental …, 2002 - Wiley Online Library
Motor development in very preterm children differs in several important ways from that of
children born at full term. Variability is common, although the anatomic and physiologic …

[HTML][HTML] Behavioural, educational and respiratory outcomes of antenatal betamethasone for term caesarean section (ASTECS trial)

PR Stutchfield, R Whitaker, AE Gliddon… - Archives of Disease in …, 2013 - fn.bmj.com
Objectives To determine whether antenatal betamethasone prior to elective term caesarean
section (CS) affects long term behavioural, cognitive or developmental outcome, and …

Antenatal exposure to betamethasone: psychological functioning and health related quality of life 31 years after inclusion in randomised controlled trial

SR Dalziel, VK Lim, A Lambert, D McCarthy, V Parag… - Bmj, 2005 - bmj.com
Objectives To determine if antenatal exposure to betamethasone for the prevention of
neonatal respiratory distress syndrome alters psychological functioning and health related …

Adverse effects of antenatal glucocorticoids on cerebral myelination in sheep

I Antonow-Schlorke, A Helgert, C Gey… - Obstetrics & …, 2009 - journals.lww.com
OBJECTIVE: To determine in fetal sheep the effect of betamethasone on myelination in
relation to stage of myelination, number of treatment courses, dose, and route of …

The increasing racial disparity in infant mortality: respiratory distress syndrome and other causes

WP Frisbie, SE Song, DA Powers, JA Street - Demography, 2004 - Springer
Although substantial declines in infant mortality rates have occurred across racial/ethnic
groups, there has been a marked increase in relative black-white disparity in the risk of …