[HTML][HTML] Recent advances in leishmaniasis treatment

TS Tiuman, AO Santos, T Ueda-Nakamura… - International Journal of …, 2011 - Elsevier
About 1.5 million new cases of cutaneous leishmaniasis and 500 000 new cases of visceral
leishmaniasis occur each year around the world. For over half a century, the clinical forms of …

Leishmaniasis: current treatment and prospects for new drugs and vaccines

L Kedzierski, A Sakthianandeswaren… - Current medicinal …, 2009 - ingentaconnect.com
Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement
and fatal systemic infection. WHO estimates that the disease results in 2 million new cases a …

Potassium phthalimide-N-oxyl: a novel, efficient, and simple organocatalyst for the one-pot three-component synthesis of various 2-amino-4H-chromene derivatives in …

MG Dekamin, M Eslami, A Maleki - Tetrahedron, 2013 - Elsevier
A wide variety of 2-amino-4H-chromene derivatives with diverse substituents on the 4H-
chromene ring were efficiently prepared via one-pot, three-component reaction of an …

Monoterpenic aldehydes as potential anti-Leishmania agents: activity of Cymbopogon citratus and citral on L. infantum, L. tropica and L. major

M Machado, P Pires, AM Dinis, M Santos-Rosa… - Experimental …, 2012 - Elsevier
In order to contribute for the search of new drugs for leishmaniasis, we study the
susceptibility of Leishmania infantum, Leishmania tropica and Leishmania major to …

Synthesis and applications of CoFe 2 O 4 nanoparticles for multicomponent reactions

JK Rajput, G Kaur - Catalysis Science & Technology, 2014 - pubs.rsc.org
An efficient, simple, green protocol is developed for the synthesis of 2-amino-4-(phenyl)-5, 6,
7, 8-tetrahydro-7, 7-dimethyl-5-oxo-4H-chromene-3-carbonitrile derivatives and 2, 2 …

Activity of Thymus capitellatus volatile extract, 1, 8-cineole and borneol against Leishmania species

M Machado, AM Dinis, M Santos-Rosa, V Alves… - Veterinary …, 2014 - Elsevier
In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (family
Lamiaceae) volatile extract and its major compounds, 1, 8-cineole and borneol, were tested …

New cycloartane triterpenoids from Dysoxylum malabaricum and their cytotoxic evaluation

N Bhardwaj, A Sharma, N Tripathi, B Goel, G Ravikanth… - Steroids, 2023 - Elsevier
The cytotoxic dichloromethane-methanol bark extract of Dysoxylum malabaricum was
subjected to bioassay-guided fractionation, followed by systematic dereplication to focus on …

Nerolidol, the main constituent of Piper aduncum essential oil, has anti-Leishmania braziliensis activity

LF Ceole, MDG Cardoso, MJ Soares - Parasitology, 2017 - cambridge.org
Leishmania (Viannia) braziliensis is a protozoan that causes mucocutaneous leishmaniasis,
which is an infectious disease that affects more than 12 million people worldwide. The …

[HTML][HTML] In vitro biological evaluation of eight different essential oils against Trypanosoma cruzi, with emphasis on Cinnamomum verum essential oil

CMO Azeredo, TG Santos, BHLNS Maia… - BMC complementary and …, 2014 - Springer
Abstract Background Essential oils (EOs) are complex mixtures of secondary metabolites
from various plants. It has been shown that several EOs, or their constituents, have inhibitory …

[HTML][HTML] Antileishmanial activity of semisynthetic lupane triterpenoids betulin and betulinic acid derivatives: synergistic effects with miltefosine

MC Sousa, R Varandas, RC Santos, M Santos-Rosa… - PloS one, 2014 - journals.plos.org
Leishmaniasis is a neglected tropical disease (NTDs), endemic in 88 countries, affecting
more than 12 million people. The treatment consists in pentavalent antimony compounds …