T cell responses to cytomegalovirus
P Klenerman, A Oxenius - Nature Reviews Immunology, 2016 - nature.com
Human cytomegalovirus (HCMV) establishes a latent infection that generally remains
asymptomatic in immune-competent hosts for decades but can cause serious illness in …
asymptomatic in immune-competent hosts for decades but can cause serious illness in …
Effects of acute and chronic exercise on immunological parameters in the elderly aged: can physical activity counteract the effects of aging?
Immunosenescence is characterized by deterioration of the immune system caused by
aging which induces changes to innate and adaptive immunity. Immunosenescence affects …
aging which induces changes to innate and adaptive immunity. Immunosenescence affects …
Dissecting human population variation in single-cell responses to SARS-CoV-2
Humans display substantial interindividual clinical variability after SARS-CoV-2 infection,–,
the genetic and immunological basis of which has begun to be deciphered. However, the …
the genetic and immunological basis of which has begun to be deciphered. However, the …
FcεRIγ-negative NK cells persist in vivo and enhance efficacy of therapeutic monoclonal antibodies in multiple myeloma
Monoclonal antibodies (mAbs) are a central component of therapy for hematologic
malignancies. Widely used mAb agents in multiple myeloma (MM) include daratumumab …
malignancies. Widely used mAb agents in multiple myeloma (MM) include daratumumab …
Adaptive NKG2C+ NK cell response and the risk of cytomegalovirus infection in kidney transplant recipients
D Redondo-Pachón, M Crespo, J Yélamos… - The Journal of …, 2017 - journals.aai.org
CMV infection in kidney transplant recipients (KTRs) has been associated with an increased
risk for graft loss and reduced host survival. CMV promotes persistent expansions of NK …
risk for graft loss and reduced host survival. CMV promotes persistent expansions of NK …
[PDF][PDF] Human cytomegalovirus infection and the immune response to exercise.
Human cytomegalovirus (HCMV) is a ubiquitous β-herpes virus that has co-evolved with its
host since the very beginning of human life. The vast majority of adults worldwide carry the …
host since the very beginning of human life. The vast majority of adults worldwide carry the …
Dual role of natural killer cells on graft rejection and control of cytomegalovirus infection in renal transplantation
M López-Botet, C Vilches, D Redondo-Pachón… - Frontiers in …, 2017 - frontiersin.org
Allograft rejection constitutes a major complication of solid organ transplantation requiring
prophylactic/therapeutic immunosuppression, which increases susceptibility of patients to …
prophylactic/therapeutic immunosuppression, which increases susceptibility of patients to …
Latent cytomegalovirus infection enhances anti-tumour cytotoxicity through accumulation of NKG2C+ NK cells in healthy humans
AB Bigley, K Rezvani, N Shah, T Sekine… - Clinical & …, 2016 - academic.oup.com
Cytomegalovirus (CMV) infection markedly expands NKG2C+/NKG2A− NK cells, which are
potent killers of infected cells expressing human leucocyte antigen (HLA)-E. As HLA-E is …
potent killers of infected cells expressing human leucocyte antigen (HLA)-E. As HLA-E is …
NKG2C+CD57+ Natural Killer Cell Expansion Parallels Cytomegalovirus‐Specific CD8+ T Cell Evolution towards Senescence
J Heath, N Newhook, E Comeau… - Journal of …, 2016 - Wiley Online Library
Objective. Measuring NKG2C+ CD57+ natural killer (NK) cell expansion to investigate NK
responses against human cytomegalovirus (HCMV) and assessing relationships with …
responses against human cytomegalovirus (HCMV) and assessing relationships with …
Natural killer cells, aging, and vaccination
Aging is associated with changes in the immune system. Both (innate and adaptive) arms of
the immune system are involved. Natural killer (NK) cells are part of the innate immune …
the immune system are involved. Natural killer (NK) cells are part of the innate immune …