Appropriate anticoagulation for hemodialysis (HD) requires a subtle balance between under‐
and over‐heparinization to prevent extracorporeal circuit (ECC) clotting and bleeding …

Calcium is a key clotting factor, and several inorganic molecules that bind to calcium have
been found to reduce the clotting propensity of blood. Citrate, a calcium chelator, is used as …

Citrate has many characteristics of the ideal anticoagulant for hemodialysis. In addition to
immediate and complete anticoagulation in the dialysis circuit, citrate has important effects …

Objective Safe and effective anticoagulation is essential for hemodialysis patients who are at
high risk of bleeding. The purpose of this trial is to evaluate the effectiveness and safety of …

Acute renal failure is a major complication of rhabdomyolysis. New membranes for
hemodialysis have been developed with a high cut‐off pore size allowing efficient removal …

Background Regional citrate anticoagulation during hemodialysis provides an immediate
and complete anticoagulant effect, which is limited to the extracorporeal circuit. Citrate has …

Background Neonates with inborn errors of metabolism (IEM) often develop
hyperammonemia which, if not corrected quickly, may result in poor neurologic outcomes …

Background Recommended regular saline flushing presents clinical ineffectiveness for
hemodialysis (HD) patients at high risk of bleeding with heparin contraindication. Regional …

Objective To evaluate the safety and effectiveness of an individualized regional citrate
anticoagulation (RCA) protocol for hemodialysis. Methods In this single-center, retrospective …

Background: The dose of citrate needed in regional citrate anticoagulation (RCA) to achieve
optimal biocompatibility is unknown. We performed a randomized trial comparing two doses …