Galectin-3 as a next-generation biomarker for detecting early stage of various diseases

A Hara, M Niwa, K Noguchi, T Kanayama, A Niwa… - Biomolecules, 2020 - mdpi.com
Galectin-3 is a β-galactoside-binding lectin which is important in numerous biological
activities in various organs, including cell proliferation, apoptotic regulation, inflammation …

[HTML][HTML] Diabetic kidney disease: An overview of prevalence, risk factors, and biomarkers

S Hussain, MC Jamali, A Habib, MS Hussain… - … and Global Health, 2021 - Elsevier
Diabetic kidney disease (DKD) is a major public health problem characterized by elevated
urine albumin excretion or reduced glomerular filtration rate or both. The pathophysiology of …

Galectin‐3 is a potential mediator for atherosclerosis

Z Gao, Z Liu, R Wang, Y Zheng, H Li… - Journal of immunology …, 2020 - Wiley Online Library
Atherosclerosis is a multifactorial chronic inflammatory arterial disease forming the
pathological basis of many cardiovascular diseases such as coronary heart disease, heart …

The role of galectins as modulators of metabolism and inflammation

MF Brinchmann, DM Patel… - Mediators of …, 2018 - Wiley Online Library
Galectins are β‐galcotosid‐binding lectins. The function of galectins varies with their tissue‐
specific and subcellular location, and their binding to carbohydrates makes them key players …

The role of galectin-3 in the kidneys

SC Chen, PL Kuo - International journal of molecular sciences, 2016 - mdpi.com
Galectin-3 is a 32-to 35-kDa member of the galectin family of b-galactoside-binding lectins,
which is characterized by a carbohydrate recognition domain. Through its carbohydrate …

[HTML][HTML] Myocardial ischemia reperfusion injury: apoptotic, inflammatory and oxidative stress role of galectin-3

S Al-Salam, S Hashmi - Cellular Physiology and Biochemistry, 2018 - karger.com
Background/Aims: Myocardial reperfusion has the potential to salvage the ischemic
myocardium after a period of coronary occlusion. Reperfusion, however, can cause a wide …

Galectin-3: an emerging all-out player in metabolic disorders and their complications

G Pugliese, C Iacobini, CM Pesce, S Menini - Glycobiology, 2015 - academic.oup.com
Galectin-3 has been increasingly recognized as an important modulator of several biological
functions, by interacting with several molecules inside and outside the cell, and an emerging …

Evolving mechanistic insights into galectin functions

CM Arthur, MD Baruffi, RD Cummings… - Galectins: Methods and …, 2015 - Springer
Galectins are an evolutionarily ancient family of glycan-binding proteins (GBPs) and are
found in all animals. Although they were discovered over 30 years ago, ideas about their …

Modified citrus pectin reduces galectin-3 expression and disease severity in experimental acute kidney injury

M Kolatsi-Joannou, KL Price, PJ Winyard, DA Long - PloS one, 2011 - journals.plos.org
Galectin-3 is a β-galactoside binding lectin with roles in diverse processes including
proliferation, apoptosis, inflammation and fibrosis which are dependent on different domains …

Relationship of plasma galectin‐3 to renal function in patients with heart failure: effects of clinical status, pathophysiology of heart failure, and presence or absence of …

DM Gopal, M Kommineni, N Ayalon… - Journal of the …, 2012 - Am Heart Assoc
Background Galectin‐3 (GAL‐3), a β‐galactoside–binding protein, is a new clinical
biomarker believed to reflect cardiac remodeling/fibrosis in patients with heart failure (HF) …