Cerebrovascular reactivity (CVR) MRI with CO2 challenge: a technical review

P Liu, B Jill, H Lu - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

Measuring cerebrovascular reactivity: what stimulus to use?

J Fierstra, O Sobczyk… - The Journal of …, 2013 - Wiley Online Library
Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory
or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between …

Cerebrovascular reactivity mapping without gas challenges: a methodological guide

J Pinto, MG Bright, DP Bulte, P Figueiredo - Frontiers in Physiology, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) is defined as the ability of vessels to alter their caliber in
response to vasoactive factors, by means of dilating or constricting, in order to increase or …

Quantitative measurement of cerebral physiology using respiratory-calibrated MRI

DP Bulte, M Kelly, M Germuska, J Xie, MA Chappell… - Neuroimage, 2012 - Elsevier
Functional magnetic resonance imaging typically measures signal increases arising from
changes in the transverse relaxation rate over small regions of the brain and associates …

Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

A review of calibrated blood oxygenation level‐dependent (BOLD) methods for the measurement of task‐induced changes in brain oxygen metabolism

NP Blockley, VEM Griffeth, AB Simon… - NMR in …, 2013 - Wiley Online Library
The dynamics of the blood oxygenation level‐dependent (BOLD) response are dependent
on changes in cerebral blood flow, cerebral blood volume and the cerebral metabolic rate of …

CO2 Blood Oxygen Level–dependent MR Mapping of Cerebrovascular Reserve in a Clinical Population: Safety, Tolerability, and Technical Feasibility

VR Spano, DM Mandell, J Poublanc, K Sam… - Radiology, 2013 - pubs.rsna.org
Purpose To evaluate the safety, tolerability, and technical feasibility of mapping
cerebrovascular reactivity (CVR) in a clinical population by using a precise prospectively …

Comparison of Cerebral Vascular Reactivity Measures Obtained Using Breath-Holding and CO2 Inhalation

FB Tancredi, RD Hoge - Journal of Cerebral Blood Flow & …, 2013 - journals.sagepub.com
Stimulation of cerebral vasculature using hypercapnia has been widely used to study
cerebral vascular reactivity (CVR), which can be expressed as the quantitative change in …

Measuring cerebrovascular reactivity: the dynamic response to a step hypercapnic stimulus

J Poublanc, AP Crawley, O Sobczyk… - Journal of Cerebral …, 2015 - journals.sagepub.com
We define cerebral vascular reactivity (CVR) as the ratio of the change in blood oxygen level-
dependent (BOLD) magnetic resonance imaging (MRI) signal (S) to an increase in blood …

Cerebrovascular reactivity across the entire brain in cerebral amyloid angiopathy

AE Beaudin, CR McCreary, EL Mazerolle, M Gee… - Neurology, 2022 - AAN Enterprises
Background and Objectives Reduced cerebrovascular reactivity is proposed to be a feature
of cerebral amyloid angiopathy (CAA) but has not been measured directly. Employing a …