Exosomes are secreted nanovesicles with potent signalling activity that are initially formed
as intraluminal vesicles (ILVs) in late Rab7‐positive multivesicular endosomes, and also in …

Exosomes are secreted extracellular vesicles carrying diverse molecular cargos, which can
modulate recipient cell behaviour. They are thought to derive from intraluminal vesicles …

Sperm competition favors large, costly ejaculates, and theory predicts the evolution of
allocation strategies that enable males to plastically tailor ejaculate expenditure to sperm …

Regulated secretion is a fundamental cellular process in which biologically active molecules
stored in long-lasting secretory granules (SGs) are secreted in response to external stimuli …

Even in well-characterized genomes, many transcripts are considered noncoding RNAs
(ncRNAs) simply due to the absence of large open reading frames (ORFs). However, it is …

Background The female reproductive tract is exposed directly to the male's ejaculate,
making it a hotspot for mating-induced responses. In Drosophila melanogaster, changes in …

Although thousands of long non-coding RNAs (lncRNA) have been identified in the
genomes of higher eukaryotes, the precise function of most of them is still unclear. Here, we …

Secretory cells in glands and the nervous system frequently package and store proteins
destined for regulated secretion in dense-core granules (DCGs), which disperse when …

Seminal fluid proteins (SFPs) exert potent effects on male and female fitness. Rapidly
evolving and molecularly diverse, they derive from multiple male secretory cells and tissues …

Highlights•Activity-dependent autocrine signals play critical roles in synaptic
plasticity.•Transient retrograde signals can activate sustained autocrine signals.•Drosophila …