Dynamic covalent chemistry

SJ Rowan, SJ Cantrill, GRL Cousins… - Angewandte Chemie …, 2002 - Wiley Online Library
Dynamic covalent chemistry relates to chemical reactions carried out reversibly under
conditions of equilibrium control. The reversible nature of the reactions introduces the …

Dynamic combinatorial chemistry

PT Corbett, J Leclaire, L Vial, KR West… - Chemical …, 2006 - ACS Publications
Dynamic combinatorial chemistry is defined as combinatorial chemistry under
thermodynamic control; that is, in a dynamic combinatorial library (DCL), all constituents are …

Dynamic combinatorial/covalent chemistry: a tool to read, generate and modulate the bioactivity of compounds and compound mixtures

A Herrmann - Chemical Society Reviews, 2014 - pubs.rsc.org
Reversible covalent bond formation under thermodynamic control adds reactivity to self-
assembled supramolecular systems, and is therefore an ideal tool to assess complexity of …

“Let's twist again” double-stranded, triple-stranded, and circular helicates

M Albrecht - Chemical reviews, 2001 - ACS Publications
A helix is a geometric motif which is found in natural as well as in artificial structures. Helicity
can be observed in the spiral arms of galaxies or in microscopic structures such as right-or …

Dynamic combinatorial chemistry and virtual combinatorial libraries

JM Lehn - Essays in Contemporary Chemistry: From Molecular …, 2001 - Wiley Online Library
Dynamic Combinatorial Chemistry and Virtual Combinatorial Libraries<link href='#fn1'></link>
Page 1 Dynamic Combinatorial Chemistry and Virtual Combinatorial Libraries 1 ) by Jean-Marie …

Fragment-based drug discovery

DA Erlanson, RS McDowell… - Journal of medicinal …, 2004 - ACS Publications
The pharmaceutical industry's ability to produce new medicines is directly tied to its success
in identifying druglike molecules that target clinically relevant pathways. As a consequence …

Drug discovery by dynamic combinatorial libraries

O Ramström, JM Lehn - Nature Reviews Drug Discovery, 2002 - nature.com
Dynamic combinatorial chemistry is a recently introduced supramolecular approach that
uses self-assembly processes to generate libraries of chemical compounds. In contrast to …

Solid-phase oligosaccharide synthesis and combinatorial carbohydrate libraries

PH Seeberger, WC Haase - Chemical reviews, 2000 - ACS Publications
The transfer of information is a fundamental process of life and central to all cellular systems.
From a biological perspective, information needs to be transmitted intracellularly and …

Dynamische kovalente Chemie

SJ Rowan, SJ Cantrill, GRL Cousins… - Angewandte …, 2002 - Wiley Online Library
Die dynamische kovalente Chemie befasst sich mit reversiblen chemischen Reaktionen, die
man unter Gleichgewichtsbedingungen ausführt. Mit der Reversibilität von Reaktionen ist …

Dynamic combinatorial chemistry

JM Lehn, AV Eliseev - Science, 2001 - science.org
Combinatorial chemistry is now widely used to generate vast libraries of molecules that can
be screened for biologically active substances and new materials. In a parallel development …