Brain function relies on the ability of neurons to communicate with each other. Interneuronal
communication primarily takes place at synapses, where information from one neuron is …

Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Gap junctions consist of arrays of intercellular channels that enable adjacent cells to
communicate both electrically and metabolically. Gap junctions have a wide diversity of …

Connexins are chordate gap junction channel proteins that, by enabling direct
communication between the cytosols of adjacent cells, create a unique cell signalling …

Mitochondria are vital organelles in cells, regulating energy metabolism and apoptosis.
Mitochondrial transcellular transfer plays a crucial role during physiological and pathological …

Electrical synapses are found in vertebrate and invertebrate nervous systems. The cellular
basis of these synapses is the gap junction, a group of intercellular channels that mediate …

Gap junctions form electrical conduits between adjacent myocardial cells, permitting rapid
spatial passage of the excitation current essential to each heartbeat. Arrhythmogenic …

In recent years our understanding of connexins has advanced from viewing them simply as
proteins with a surprisingly short lifespan that form gap junction channels. Connexins are …

Gap junctions (GJs) are the only known cellular structures that allow a direct cell-to-cell
transfer of signaling molecules by forming densely packed arrays or “plaques” of hydrophilic …