Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications
WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …
because of their high immunomodulation ability, tropism towards inflamed and injured …
Mechanisms of mesenchymal stem/stromal cell function
JL Spees, RH Lee, CA Gregory - Stem cell research & therapy, 2016 - Springer
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …
Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells
X Wang, HH Gerdes - Cell Death & Differentiation, 2015 - nature.com
Tunneling nanotubes (TNTs) are F-actin-based membrane tubes that form between cells in
culture and in tissues. They mediate intercellular communication ranging from electrical …
culture and in tissues. They mediate intercellular communication ranging from electrical …
Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies
M Tardivel, S Bégard, L Bousset, S Dujardin… - Acta neuropathologica …, 2016 - Springer
A given cell makes exchanges with its neighbors through a variety of means ranging from
diffusible factors to vesicles. Cells use also tunneling nanotubes (TNTs), filamentous-actin …
diffusible factors to vesicles. Cells use also tunneling nanotubes (TNTs), filamentous-actin …
Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes
S Abounit, L Bousset, F Loria, S Zhu… - The EMBO …, 2016 - embopress.org
Synucleinopathies such as Parkinson's disease are characterized by the pathological
deposition of misfolded α‐synuclein aggregates into inclusions throughout the central and …
deposition of misfolded α‐synuclein aggregates into inclusions throughout the central and …
Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance
Our vision of cancer has changed during the past decades. Indeed tumors are now
perceived as complex entities where tumoral and stromal components interact closely …
perceived as complex entities where tumoral and stromal components interact closely …
Tunneling nanotubes and gap junctions–their role in long-range intercellular communication during development, health, and disease conditions
J Ariazi, A Benowitz, V De Biasi… - Frontiers in molecular …, 2017 - frontiersin.org
Cell-to-cell communication is essential for the organization, coordination, and development
of cellular networks and multi-cellular systems. Intercellular communication is mediated by …
of cellular networks and multi-cellular systems. Intercellular communication is mediated by …
Peering into tunneling nanotubes—The path forward
D Cordero Cervantes, C Zurzolo - The EMBO journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …
Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma
E Lou, S Fujisawa, A Morozov, A Barlas, Y Romin… - PloS one, 2012 - journals.plos.org
Tunneling nanotubes are long, non-adherent F-actin-based cytoplasmic extensions which
connect proximal or distant cells and facilitate intercellular transfer. The identification of …
connect proximal or distant cells and facilitate intercellular transfer. The identification of …
Inter and Intracellular mitochondrial trafficking in health and disease
S Shanmughapriya, D Langford… - Ageing research …, 2020 - Elsevier
Neurons and glia maintain central nervous system (CNS) homeostasis through diverse
mechanisms of intra-and intercellular signaling. Some of these interactions include the …
mechanisms of intra-and intercellular signaling. Some of these interactions include the …