Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Spatiotemporal Immune disorder is a key factor leading to the failure of bone tissue healing.
It is of vital importance to accurately suppress excessive peak immune response within 24 …

Ischemic diseases lead to considerable morbidity and mortality, yet conventional clinical
treatment strategies for therapeutic angiogenesis fall short of being impactful. Despite the …

Critical limb ischemia (CLI) is a serious form of peripheral arterial disease that involves
severe blockage of blood flow in lower extremities, often leading to foot necrosis and limb …

Therapeutic angiogenesis is a promising approach for the treatment of critical limb ischemia
(CLI), but always face failure in clinical trials. The existing strategies primarily regulate a …

Microporosity in hydrogels is critical for directing tissue formation and function. We have
developed a fibrin-based smart hydrogel, termed an acoustically responsive scaffold (ARS) …

Acoustic droplet vaporization (ADV) is the phase-transitioning of perfluorocarbon emulsions,
termed phase-shift emulsions, into bubbles using focused ultrasound. ADV has been utilized …

Phase-shift droplets are a highly adaptable platform for biomedical applications of
ultrasound. The spatiotemporal response of phase-shift droplets to focused ultrasound …