Abstract In 1982, the Food and Drug Administration (FDA) of the United States of America
approved isotretinoin (13-cis-retinoic acid), a retinoid derivative of vitamin A, to treat severe …

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with
recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact …

4 Armstrong AW, Chambers CJ, Maverakis E et al. Effectiveness of online vs in-person care
for adults with psoriasis: a randomized clinical trial. JAMA Netw Open 2018; 1: e183062. 5 …

Background: Isotretinoin is a synthetic retinoid, derived from vitamin A, with multiple
mechanisms of action and highly effective in the treatment of acne, despite common adverse …

While isotretinoin has been the gold-standard of therapy for severe acne since its approval
in 1982, its anti-inflammatory properties makes it a potentially applicable and versatile …

This systematic review identifies and critically evaluates the mechanistic and clinical
evidence of new promising therapeutic targets in hidradenitis suppurativa (HS). Evidence for …

Hidradenitis suppurativa is a chronic disease of the pilosebaceous unit. The name of the
condition is a testament to the presumed relationship between the disease and the …

Hidradenitis suppurativa is a chronic inflammatory skin disorder primarily affecting apocrine
gland-bearing areas, including the axillae, groin, and buttocks. It is reported in up to 2% of …

Isotretinoin is a first‐generation retinoid initially approved for the treatment of severe cases
of acne vulgaris (nodulocystic acne). Because of its broad anti‐inflammatory and …

Hidradenitis suppurativa is a chronic inflammatory disease that disproportionately affects
women of childbearing age. Hidradenitis suppurativa is characterized by painful nodules …