Beneficial properties of bromelain

P Hikisz, J Bernasinska-Slomczewska - Nutrients, 2021 - mdpi.com
Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having
multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high …

Bromelain and nisin: The natural antimicrobials with high potential in biomedicine

U Jančič, S Gorgieva - Pharmaceutics, 2021 - mdpi.com
Infectious diseases along with various cancer types are among the most significant public
health problems and the leading cause of death worldwide. The situation has become even …

Anticancer properties of bromelain: State-of-the-art and recent trends

R Pezzani, M Jimenez-Garcia, X Capo… - Frontiers in …, 2023 - frontiersin.org
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …

Anticancer activities of biogenic silver nanoparticles targeting apoptosis and inflammatory pathways in colon cancer cells

VR Narasimha, TS Latha, R Pallu, K Panati… - Journal of Cluster …, 2022 - Springer
Colorectal cancer (CRC) progression is a complex process, with an interplay of multiple
molecular signaling pathways. Cyclooxygenase-2 (COX-2) and NF-κB are important …

Proteins and their functionalization for finding therapeutic avenues in cancer: Current status and future prospective

S Mohanty, S Panda, U Devadharshini… - Biochimica et Biophysica …, 2023 - Elsevier
Despite the remarkable advancement in the health care sector, cancer remains the second
most fatal disease globally. The existing conventional cancer treatments primarily include …

Green synthesis of novel selenium nanoparticles using Crataegus monogyna extract (SeNPs@CM) and investigation of its toxicity, antioxidant capacity, and …

F Barzegarparay, H Najafzadehvarzi… - Biomass Conversion …, 2023 - Springer
In recent years, the synthesis of nanoparticles using bioactive agent, the so-called green
synthesis, has attracted scientist's attentions due to their unique potentials. Since breast …

Controlling the size, shape, and stability of SeNPs by bromelain: Improved antioxidant, anti-bacterial and anti-cancer activities

S Bibi, A Munawar, MW Ishaq, F Zaman, M Abid… - Journal of molecular …, 2024 - Elsevier
Selenium nanoparticles (SeNPs) are of great interest due to their pharmaceutical
importance. We describe an advanced procedure to prepare highly stable SeNPs with …

Cytotoxic effect of bromelain on HepG2 hepatocellular carcinoma cell line

SS Murthy, TB Narsaiah - Applied Biochemistry and Biotechnology, 2021 - Springer
Cancer is a complicated long-term disease due to computable key molecular players
involved in aggravating the disease. Among various kinds of cancer, hepatocellular …

A comprehensive overview on the anti-inflammatory, antitumor, and ferroptosis functions of bromelain: an emerging cysteine protease

PK Rajan, NR Dunna… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Bromelain belongs to the cysteine protease endopeptidase class of enzymes
isolated from the stem and fruit tissue component of Ananas comosus. The commercial and …

The survey of antitumor effects of bromelain on neoplastic breast cells: A systematic review

MR Khosravi, E Raeisi… - Journal of …, 2024 - herbmedpharmacol.com
Background: Breast cancer is one of the most prevalent cancers in women worldwide.
Considering the side effects of chemotherapy treatments, we investigated the anticancer …