[HTML][HTML] Targeting signaling pathways in prostate cancer: mechanisms and clinical trials
Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …
genomic landscapes and biological functions, the treatment of PCa continues to improve …
The interactions of docetaxel with tumor microenvironment
R Gupta, MM Kadhim, AT Jalil, MQ Alasheqi… - International …, 2023 - Elsevier
There are several interactions within the tumor microenvironment (TME) that affect the
response of cancer cells to therapy. There are also a large number of cells and secretions in …
response of cancer cells to therapy. There are also a large number of cells and secretions in …
[HTML][HTML] Future regenerative medicine developments and their therapeutic applications
Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …
[HTML][HTML] Stromal cells in prostate cancer pathobiology: friends or foes?
F Pederzoli, M Raffo, H Pakula, F Ravera… - British Journal of …, 2023 - nature.com
The genomic, epigenetic and metabolic determinants of prostate cancer pathobiology have
been extensively studied in epithelial cancer cells. However, malignant cells constantly …
been extensively studied in epithelial cancer cells. However, malignant cells constantly …
[HTML][HTML] Emerging role of IGF-1 in prostate cancer: a promising biomarker and therapeutic target
G Liu, M Zhu, M Zhang, F Pan - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer (PCa) affects millions of men globally, and approximately
20% of PCa patients are found after they develop into a lethal metastatic or castration …
20% of PCa patients are found after they develop into a lethal metastatic or castration …
Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling
Prostate cancer (PC) is the most frequently diagnosed malignancy and a leading cause of
cancer deaths in US men. Many PC cases metastasize and develop resistance to systemic …
cancer deaths in US men. Many PC cases metastasize and develop resistance to systemic …
[HTML][HTML] Role of bFGF in acquired resistance upon anti-VEGF therapy in cancer
FT Zahra, MS Sajib, CM Mikelis - Cancers, 2021 - mdpi.com
Simple Summary Anti-angiogenic therapies targeting the vascular endothelial growth factor
(VEGF) signaling are established in the arsenal of cancer treatments. Despite the …
(VEGF) signaling are established in the arsenal of cancer treatments. Despite the …
[HTML][HTML] Angioprevention of urologic cancers by plant-derived foods
M García-Caballero, JA Torres-Vargas, AD Marrero… - Pharmaceutics, 2022 - mdpi.com
The number of cancer cases worldwide keeps growing unstoppably, despite the undeniable
advances achieved by basic research and clinical practice. Urologic tumors, including some …
advances achieved by basic research and clinical practice. Urologic tumors, including some …
[HTML][HTML] Advances in landscape and related therapeutic targets of the prostate tumor microenvironment: Therapeutic targets of the prostate tumor microenvironment
The distinct tumor microenvironment (TME) of prostate cancer (PCa), which promotes tumor
proliferation and progression, consists of various stromal cells, immune cells, and a dense …
proliferation and progression, consists of various stromal cells, immune cells, and a dense …
[HTML][HTML] Three-dimensional growth of prostate cancer cells exposed to simulated microgravity
Prostate cancer metastasis has an enormous impact on the mortality of cancer patients.
Factors involved in cancer progression and metastasis are known to be key players in …
Factors involved in cancer progression and metastasis are known to be key players in …