Regulation of the master regulator FOXM1 in cancer

GB Liao, XZ Li, S Zeng, C Liu, SM Yang, L Yang… - Cell Communication and …, 2018 - Springer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …

[HTML][HTML] Dysregulated FOXM1 signaling in the regulation of cancer stem cells

G Sher, T Masoodi, K Patil, S Akhtar… - Seminars in cancer …, 2022 - Elsevier
Since the introduction of the cancer stem cell (CSC) paradigm, significant advances have
been made in understanding the functional and biological plasticity of these elusive …

Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis

VHL Nguyen, R Hough, S Bernaudo, C Peng - Journal of ovarian research, 2019 - Springer
Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/β-catenin
pathway plays critical roles in regulating embryonic development and physiological …

Pan-cancer analyses reveal genomic features of FOXM1 overexpression in cancer

CJ Barger, C Branick, L Chee, AR Karpf - Cancers, 2019 - mdpi.com
FOXM1 is frequently overexpressed in cancer, but this has not been studied in a
comprehensive manner. We utilized genotype-tissue expression (GTEx) normal and The …

FOXM1: A small fox that makes more tracks for cancer progression and metastasis

MA Khan, P Khan, A Ahmad, M Fatima… - Seminars in Cancer …, 2023 - Elsevier
Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …

Recent advances in ovarian cancer: therapeutic strategies, potential biomarkers, and technological improvements

S Akter, MA Rahman, MN Hasan, H Akhter, P Noor… - Cells, 2022 - mdpi.com
Aggressive and recurrent gynecological cancers are associated with worse prognosis and a
lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in …

FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy

J Lin, W Wang, T Hu, G Zhu, L Li, C Zhang, Z Xu, H Yu… - Cancer Letters, 2020 - Elsevier
Docetaxel-mediated chemotherapy is the first line therapy for metastatic castration-resistant
prostate cancer (CRPC) patients, but its therapeutic benefit is limited by the development of …

FOXM1: a multifunctional oncoprotein and emerging therapeutic target in ovarian cancer

C Liu, CJ Barger, AR Karpf - Cancers, 2021 - mdpi.com
Simple Summary Ovarian cancer is a lethal disease in women with a 10-year survival rate
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …

DREAM on: cell cycle control in development and disease

H Walston, AN Iness, L Litovchick - Annual review of genetics, 2021 - annualreviews.org
Perfectly orchestrated periodic gene expression during cell cycle progression is essential for
maintaining genome integrity and ensuring that cell proliferation can be stopped by …

The dominant role of forkhead box proteins in cancer

DH Bach, NP Long, TTT Luu, NH Anh… - International journal of …, 2018 - mdpi.com
Forkhead box (FOX) proteins are multifaceted transcription factors that are significantly
implicated in cancer, with various critical roles in biological processes. Herein, we provide …