Regulation of the master regulator FOXM1 in cancer
GB Liao, XZ Li, S Zeng, C Liu, SM Yang, L Yang… - Cell Communication and …, 2018 - Springer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …
[HTML][HTML] Dysregulated FOXM1 signaling in the regulation of cancer stem cells
Since the introduction of the cancer stem cell (CSC) paradigm, significant advances have
been made in understanding the functional and biological plasticity of these elusive …
been made in understanding the functional and biological plasticity of these elusive …
Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis
VHL Nguyen, R Hough, S Bernaudo, C Peng - Journal of ovarian research, 2019 - Springer
Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/β-catenin
pathway plays critical roles in regulating embryonic development and physiological …
pathway plays critical roles in regulating embryonic development and physiological …
Pan-cancer analyses reveal genomic features of FOXM1 overexpression in cancer
FOXM1 is frequently overexpressed in cancer, but this has not been studied in a
comprehensive manner. We utilized genotype-tissue expression (GTEx) normal and The …
comprehensive manner. We utilized genotype-tissue expression (GTEx) normal and The …
FOXM1: A small fox that makes more tracks for cancer progression and metastasis
Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …
pathways associated with normal cell homeostasis and disease conditions. Among cancer …
Recent advances in ovarian cancer: therapeutic strategies, potential biomarkers, and technological improvements
Aggressive and recurrent gynecological cancers are associated with worse prognosis and a
lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in …
lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in …
FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy
J Lin, W Wang, T Hu, G Zhu, L Li, C Zhang, Z Xu, H Yu… - Cancer Letters, 2020 - Elsevier
Docetaxel-mediated chemotherapy is the first line therapy for metastatic castration-resistant
prostate cancer (CRPC) patients, but its therapeutic benefit is limited by the development of …
prostate cancer (CRPC) patients, but its therapeutic benefit is limited by the development of …
FOXM1: a multifunctional oncoprotein and emerging therapeutic target in ovarian cancer
Simple Summary Ovarian cancer is a lethal disease in women with a 10-year survival rate
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …
DREAM on: cell cycle control in development and disease
Perfectly orchestrated periodic gene expression during cell cycle progression is essential for
maintaining genome integrity and ensuring that cell proliferation can be stopped by …
maintaining genome integrity and ensuring that cell proliferation can be stopped by …
The dominant role of forkhead box proteins in cancer
Forkhead box (FOX) proteins are multifaceted transcription factors that are significantly
implicated in cancer, with various critical roles in biological processes. Herein, we provide …
implicated in cancer, with various critical roles in biological processes. Herein, we provide …