RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation

LJ Sparvero, D Asafu-Adjei, R Kang, D Tang… - Journal of translational …, 2009 - Springer
Abstract The Receptor for Advanced Glycation Endproducts [RAGE] is an evolutionarily
recent member of the immunoglobulin super-family, encoded in the Class III region of the …

[HTML][HTML] Binding of S100 proteins to RAGE: an update

E Leclerc, G Fritz, SW Vetter, CW Heizmann - Biochimica et Biophysica …, 2009 - Elsevier
The Receptor for Advanced Glycation Endproducts (RAGE) is a multi-ligand receptor of the
immunoglobulin family. RAGE interacts with structurally different ligands probably through …

Integrated single-cell and bulk RNA sequencing analysis identifies a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses …

H Zheng, H Liu, Y Ge, X Wang - Cancer cell international, 2021 - Springer
Abstract Background Cancer-associated fibroblasts (CAFs) contribute notably to colorectal
cancer (CRC) tumorigenesis, stiffness, angiogenesis, immunosuppression and metastasis …

Molecular characteristics of RAGE and advances in small-molecule inhibitors

HJ Kim, MS Jeong, SB Jang - International journal of molecular sciences, 2021 - mdpi.com
Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin
superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage …

Secretion without golgi

I Prudovsky, F Tarantini, M Landriscina… - Journal of cellular …, 2008 - Wiley Online Library
A growing number of proteins devoid of signal peptides have been demonstrated to be
released through the non‐classical pathways independent of endoplasmic reticulum and …

Placenta transcriptome profiling in intrauterine growth restriction (IUGR)

M Majewska, A Lipka, L Paukszto… - International journal of …, 2019 - mdpi.com
Intrauterine growth restriction (IUGR) is a serious pathological complication associated with
compromised fetal development during pregnancy. The aim of the study was to broaden …

Calprotectin, calgranulin C, and other members of the s100 protein family in inflammatory bowel disease

AC Manolakis, AN Kapsoritakis, EK Tiaka… - Digestive diseases and …, 2011 - Springer
Background Since their discovery, S100 proteins have been associated with diverse
diseases of inflammatory, degenerative, or malignant nature. Due to their participation in …

[HTML][HTML] The role of the S100 protein family in glioma

H Wang, X Mao, L Ye, H Cheng, X Dai - Journal of Cancer, 2022 - ncbi.nlm.nih.gov
The S100 protein family consists of 25 members and share a common structure defined in
part by the Ca 2+ binding EF-hand motif. Multiple members' dysregulated expression is …

Fine-needle aspiration of thyroid nodules: proteomic analysis to identify cancer biomarkers

L Giusti, P Iacconi, F Ciregia… - Journal of proteome …, 2008 - ACS Publications
At present, the clinical and pathological analysis used in the diagnosis of papillary thyroid
cancer (PTC) are insufficient to discern tumor behavior, and new diagnostic and prognostic …

[PDF][PDF] The importance of Ca2+/Zn2+ signaling S100 proteins and RAGE in translational medicine

E Leclerc, CW Heizmann - Front Biosci (Schol Ed), 2011 - article.imrpress.com
Introduction 3. General features of S100 proteins 4. The receptor for advanced glycation
endproducts (RAGE) 5. Structures and functions of S100 proteins and RAGE: association …