Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear

HC Pape, D Pare - Physiological reviews, 2010 - journals.physiology.org
The last 10 years have witnessed a surge of interest for the mechanisms underlying the
acquisition and extinction of classically conditioned fear responses. In part, this results from …

[HTML][HTML] MAP/ERK signaling in developing cognitive and emotional function and its effect on pathological and neurodegenerative processes

H Albert-Gascó, F Ros-Bernal… - International journal of …, 2020 - mdpi.com
The signaling pathway of the microtubule-associated protein kinase or extracellular
regulated kinase (MAPK/ERK) is a common mechanism of extracellular information …

Neural and cellular mechanisms of fear and extinction memory formation

CA Orsini, S Maren - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Over the course of natural history, countless animal species have evolved adaptive
behavioral systems to cope with dangerous situations and promote survival. Emotional …

AMPA receptor trafficking and the mechanisms underlying synaptic plasticity and cognitive aging

JM Henley, KA Wilkinson - Dialogues in clinical neuroscience, 2013 - Taylor & Francis
Even in healthy individuals there is an inexorable agerelated decline in cognitive function.
This is due, in large part, to reduced synaptic plasticity caused by changes in the molecular …

The activity-regulated cytoskeletal-associated protein (Arc/Arg3. 1) is required for memory consolidation of pavlovian fear conditioning in the lateral amygdala

JE Ploski, VJ Pierre, J Smucny, K Park… - Journal of …, 2008 - Soc Neuroscience
The activity-regulated cytoskeletal-associated protein (Arc/Arg3. 1) is an immediate early
gene that has been widely implicated in hippocampal-dependent learning and memory and …

Pavlovian fear memory circuits and phenotype models of PTSD

LR Johnson, J McGuire, R Lazarus, AA Palmer - Neuropharmacology, 2012 - Elsevier
Pavlovian fear conditioning, also known as classical fear conditioning is an important model
in the study of the neurobiology of normal and pathological fear. Progress in the …

[HTML][HTML] The mammalian START domain protein family in lipid transport in health and disease

BJ Clark - Journal of Endocrinology, 2012 - joe.bioscientifica.com
The gonadotropin FSH plays a key role in the control of Sertoli cell function. The FSH
molecular mechanism of action is best recognized for its stimulation of the adenylyl …

Nuclear protein phosphatase-1: an epigenetic regulator of fear memory and amygdala long-term potentiation

K Koshibu, J Gräff, IM Mansuy - Neuroscience, 2011 - Elsevier
Complex brain diseases and neurological disorders in human generally result from the
disturbance of multiple genes and signaling pathways. These disturbances may derive from …

Repetitive acute intermittent hypoxia increases expression of proteins associated with plasticity in the phrenic motor nucleus

I Satriotomo, EA Dale, JM Dahlberg, GS Mitchell - Experimental neurology, 2012 - Elsevier
Acute intermittent hypoxia (AIH) initiates plasticity in respiratory motor control, including
phrenic long term facilitation (pLTF). Since pLTF is enhanced by preconditioning with …

[HTML][HTML] Systemic inflammation suppresses spinal respiratory motor plasticity via mechanisms that require serine/threonine protein phosphatase activity

A Tadjalli, YB Seven, RR Perim, GS Mitchell - Journal of …, 2021 - Springer
Background Inflammation undermines multiple forms of neuroplasticity. Although
inflammation and its influence on plasticity in multiple neural systems has been extensively …