Quinoa (Chenopodium quinoa Willd.) was known as the “golden grain” by the native
Andean people in South America, and has been a source of valuable food over thousands …

Natural pentacyclic triterpenoids (PTs) have been often reported to exhibit a wide range of
biological activities. Among them, the anticancer and anti-inflammatory activities are the …

Autophagy inhibition has been demonstrated to increase the efficacy of conventional
chemotherapy. In this study, we identified hederagenin, a triterpenoid derived from Hedera …

Amides and rhodamine B conjugates of different pentacyclic triterpene acids have been
shown outstanding cytotoxicity for human tumor cells. Starting from asiatic acid, a new …

Hederagenin (HG) is a pentacyclic triterpenoid that exists in many plants in the form (s) of
sapogenin or saponins. This review highlights the pharmacokinetics, pharmacological …

Background: Sarcocephalus pobeguinii (Hua ex Pobég) is used in folk medicine to treat
oxidative-stress related diseases, thereby warranting the investigation of its anticancer and …

This review comprehensively describes the recent advances in the synthesis and
pharmacological evaluation of steroid polyamines squalamine, trodusquemine, ceragenins …

Abstract Human carboxylesterase 2 (hCE2), one of the major carboxylesterases in the
human intestine and various tumour tissues, plays important roles in the oral bioavailability …

A triterpenoid isolated from the plant Hedera helix, hederagenin was discovered to have anti-
cancer, anti-inflammatory, anti-depressant and anti-fibrosis properties both in vivo and in …

Hederagenin is a pentacyclic triterpenoid that is widely distributed as the main
pharmaceutical ingredient in various medicinal plants. Similarly as other pentacyclic …