CD146 was originally identified as a melanoma cell adhesion molecule (MCAM) and highly
expressed in many tumors and endothelial cells. However, the evidence that CD146 acts as …

The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

Immune dysfunction may contribute to tumor progression in gastric cancer (GC) patients.
One mechanism of immune dysfunction is the suppression of T cell activation and …

S100A8 and S100A9 are EF-hand Ca2+ binding proteins belonging to the S100 family.
They are abundant in cytosol of phagocytes and play critical roles in numerous cellular …

The complex formed by two members of the S100 calcium-binding protein family,
S100A8/A9, exerts apoptosis-inducing activity against various cells, especially tumor cells …

S100 proteins, a multigenic family of calcium-binding proteins, have been linked to human
pathologies in recent years. Deregulated expression of S100 proteins, including S100A8 …

Pancreatic cancer is a rapidly fatal disease, and there is an urgent need for early detection
markers and novel therapeutic targets. The current study has used a proteomic approach of …

Spatially resolved transcriptomics (SRT) technology enables us to gain novel insights into
tissue architecture and cell development, especially in tumors. However, lacking …

Purpose: S100 proteins comprise a family of calcium-modulated proteins that have recently
been associated with epithelial tumors. We examined the expression of two members of this …

Communication between cancer cells and stromal cells, often mediated by extracellular
molecules in the tumor microenvironment, plays a central role in tumorigenesis and …