Molecular and cellular mechanisms linking air pollution and bone damage

D Prada, G López, H Solleiro-Villavicencio… - Environmental …, 2020 - Elsevier
Air pollution is the second most important risk factor associated with noncommunicable
diseases after smoking. The effects of pollution on health are commonly attributable to …

Pseudarthrosis of the cervical spine

SL Zuckerman, CJ Devin - Clinical spine surgery, 2022 - journals.lww.com
Pseudarthrosis of the cervical spine represents a common and challenging problem for
spine surgeons. Rates vary greatly from as low as 0%–20% to> 60% and depend heavily on …

3D-printed ceramic-demineralized bone matrix hyperelastic bone composite scaffolds for spinal fusion

JA Driscoll, R Lubbe, AE Jakus, K Chang… - … Engineering Part A, 2020 - liebertpub.com
Although numerous spinal biologics are commercially available, a cost-effective and safe
bone graft substitute material for spine fusion has yet to be proven. In this study,“3D-Paints” …

Osteoinductivity and biomechanical assessment of a 3D printed demineralized bone matrix-ceramic composite in a rat spine fusion model

MA Plantz, S Minardi, JG Lyons, AC Greene… - Acta biomaterialia, 2021 - Elsevier
We recently developed a recombinant growth factor-free bone regenerative scaffold
composed of stoichiometric hydroxyapatite (HA) ceramic particles and human demineralized …

Bone and bone marrow disruption by endocrine‐active substances

D Agas, G Lacava, MG Sabbieti - Journal of cellular physiology, 2019 - Wiley Online Library
Bone is a multifaceted dynamic tissue, involved in mobility, mineral metabolism, and
mesenchymal or stromal and hematopoietic progenitor or stem cells breading. Recently, an …

Influence of Geometry and Architecture on the In Vivo Success of 3D-Printed Scaffolds for Spinal Fusion

M Hallman, JA Driscoll, R Lubbe, S Jeong… - … Engineering Part A, 2021 - liebertpub.com
We previously developed a recombinant growth factor-free, three-dimensional (3D)-printed
material comprising hydroxyapatite (HA) and demineralized bone matrix (DBM) for bone …

[HTML][HTML] Benzo [a] pyrene injures BMP2-induced osteogenic differentiation of mesenchymal stem cells through AhR reducing BMPRII

L An, Q Shi, M Fan, G Huang, M Zhu, M Zhang… - Ecotoxicology and …, 2020 - Elsevier
Abstract Benzo [a] pyrene (BaP), a polycyclic aromatic hydrocarbons (PAH) of environmental
pollutants, is one of the main ingredients in cigarettes and an agonist of the aryl hydrocarbon …

Variables prognostic for delayed union and nonunion following ulnar shortening fixed with a dedicated osteotomy plate

MP Gaspar, PM Kane, RC Zohn, T Buckley… - The Journal of Hand …, 2016 - Elsevier
Purpose To examine potential risk factors for the development of delayed or nonunion
following elective ulnar shortening osteotomy using a dedicated osteotomy plating system …

Environmental factors impacting bone-relevant chemokines

JT Smith, AD Schneider, KM Katchko, C Yun… - Frontiers in …, 2017 - frontiersin.org
Chemokines play an important role in normal bone physiology and the pathophysiology of
many bone diseases. The recent increased focus on the individual roles of this class of …

Aryl hydrocarbon receptor antagonists mitigate the effects of dioxin on critical cellular functions in differentiating human osteoblast-like cells

C Yun, KM Katchko, MS Schallmo, S Jeong… - International journal of …, 2018 - mdpi.com
The inhibition of bone healing in humans is a well-established effect associated with
cigarette smoking, but the underlying mechanisms are still unclear. Recent work using …