Dry coating technique has been widely used in reducing cohesion in fine cohesive
pharmaceutical powder particles and hence improving flowability. This paper aims at …

Context: Continuous processing is an innovative production concept well known and
successfully used in other industries for many years. The modern pharmaceutical industry is …

Continuous manufacturing of tablets has many advantages, including batch size flexibility,
demand-adaptive scale up or scale down, consistent product quality, small operational foot …

The improvements in the flow and packing of fine pharmaceutical powder blends due to dry
coating of micronized acetaminophen (mAPAP,∼ 11 μm), a model poorly flowing drug, are …

Optimized physical properties (eg, bulk, surface/interfacial, and mechanical properties) of
active pharmaceutical ingredients (APIs) are key to the successful integration of drug …

In this work, we have quantified effects of moisture content, over the relative humidity (RH)
range of 5–92% corresponding to 1.6–10.9% of water content, on flow properties of a grade …

Direct compaction (DC) is the preferred method for tablet production. However, only a
minority of the active pharmaceutical ingredients (APIs) can be truly manufactured into …

Fine and ultrafine particles possess great potential for industrial applications ascribed from
their huge specific surface area and ability to provide good gas–solid contact. However …

The conical screen mill or Comil, a powder delumping device, was investigated due to its
recent success as a continuously operated dry coater. The improvements in packing and …

Amorphous silica has been produced from some agricultural wastes but with drawbacks on
agglomeration challenges. In the present study, potential of maize stalk (MS) wastes as a …