[PDF][PDF] Congenital hyperinsulinism: diagnosis and treatment update

H Demirbilek, K Hussain - Journal of clinical research in …, 2017 - jag.journalagent.com
Pancreatic β-cells are finely tuned to secrete insulin so that plasma glucose levels are
maintained within a narrow physiological range (3.5-5.5 mmol/L). Hyperinsulinaemic …

Therapies and outcomes of congenital hyperinsulinism‐induced hypoglycaemia

I Banerjee, M Salomon‐Estebanez, P Shah… - Diabetic …, 2019 - Wiley Online Library
Congenital hyperinsulinism is a rare disease, but is the most frequent cause of persistent
and severe hypoglycaemia in early childhood. Hypoglycaemia caused by excessive and …

eLearning acceptance and adoption challenges in Higher Education

S Ahmad, AS Mohd Noor, AA Alwan, Y Gulzar… - Sustainability, 2023 - mdpi.com
Online learning and technology acceptance has become a highly significant subject in the
field of information technology. The challenges of eLearning acceptance and adoption in …

Surgical treatment of congenital hyperinsulinism: results from 500 pancreatectomies in neonates and children

NS Adzick, DD De Leon, LJ States, K Lord… - Journal of pediatric …, 2019 - Elsevier
Abstract Background Congenital Hyperinsulinism (HI) causes severe hypoglycemia in
neonates and children. We reviewed our experience with pancreatectomy for the various …

Standardised practices in the networked management of congenital hyperinsulinism: a UK national collaborative consensus

MG Shaikh, AK Lucas-Herald, A Dastamani… - Frontiers in …, 2023 - frontiersin.org
Congenital hyperinsulinism (CHI) is a condition characterised by severe and recurrent
hypoglycaemia in infants and young children caused by inappropriate insulin over …

Hyperinsulinemic hypoglycemia in children and adolescents: recent advances in understanding of pathophysiology and management

M Gϋemes, SA Rahman, RR Kapoor… - Reviews in Endocrine …, 2020 - Springer
Hyperinsulinemic hypoglycemia (HH) is characterized by unregulated insulin release,
leading to persistently low blood glucose concentrations with lack of alternative fuels, which …

[HTML][HTML] International guidelines for the diagnosis and management of hyperinsulinism

DD De Leon, JB Arnoux, I Banerjee, I Bergada… - Hormone Research in …, 2024 - karger.com
Background: Hyperinsulinism (HI) due to dysregulation of pancreatic beta-cell insulin
secretion is the most common and most severe cause of persistent hypoglycemia in infants …

High risk of diabetes and neurobehavioral deficits in individuals with surgically treated hyperinsulinism

K Lord, J Radcliffe, PR Gallagher… - The Journal of …, 2015 - academic.oup.com
Context: Children with the most common and severe type of congenital hyperinsulinism (HI)
frequently require pancreatectomy to control the hypoglycemia. Pancreatectomy increases …

Congenital hyperinsulinism: recent updates on molecular mechanisms, diagnosis and management

D Giri, K Hawton, S Senniappan - Journal of Pediatric Endocrinology …, 2022 - degruyter.com
Congenital hyperinsulinism (CHI) is a rare disease characterized by an unregulated insulin
release, leading to hypoglycaemia. It is the most frequent cause of persistent and severe …

Clinical practice guidelines for congenital hyperinsulinism

T Yorifuji, R Horikawa, T Hasegawa… - clinical pediatric …, 2017 - jstage.jst.go.jp
Congenital hyperinsulinism is a rare condition, and following recent advances in diagnosis
and treatment, it was considered necessary to formulate evidence-based clinical practice …