Importance Stem cell therapy is a promising treatment strategy for patients with heart failure,
which accounts for more than 10% of deaths in the United States annually. Despite more …

Rationale: Notwithstanding the uncertainties about the outcomes of bone marrow cell (BMC)
therapy for heart repair, further insights are critically needed to improve this promising …

1.1. Methodology and Evidence Review The recommendations listed in this document are,
whenever possible, evidence based. The current document constitutes a full revision and …

Rationale: The meta-Analysis of Cell-based CaRdiac study is the first prospectively declared
collaborative multinational database, including individual data of patients with ischemic …

Context Clinical trial results suggest that intracoronary delivery of autologous bone marrow
mononuclear cells (BMCs) may improve left ventricular (LV) function when administered …

For decades, mesenchymal stem (MSCs) cells have been used for cardiovascular diseases
as regenerative therapy. This review is an attempt to summarize the types of MSCs involved …

The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

After the onset of ischemia, cardiac or skeletal muscle undergoes a continuum of molecular,
cellular, and extracellular responses that determine the function and the remodeling of the …

Background Cell transplantation offers a potential therapeutic approach to the repair and
regeneration of damaged vascular and cardiac tissue after acute myocardial infarction (AMI) …

Based on the increasingly understood regenerative capacity of the human heart and
vascular system, 1 cardiovascular regenerative medicine (CRM) encompasses all potential …