Baicalein as promising anticancer agent: A comprehensive analysis on molecular mechanisms and therapeutic perspectives
AKMH Morshed, S Paul, A Hossain, T Basak… - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a multifactorial disease characterized by excessive cell
proliferation in a specific organ. The most common treatments include chemotherapy …
proliferation in a specific organ. The most common treatments include chemotherapy …
Ethnopharmacologically important highly subsidized Indian medicinal plants: systematic review on their traditional uses, phytochemistry, pharmacology, quality control …
G Aggarwal, M Sharma, R Singh, U Sharma - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance India has an extensive reservoir of traditional wisdom and
a diverse range of medicinal plants that enrich its heritage. Plants have actively been used …
a diverse range of medicinal plants that enrich its heritage. Plants have actively been used …
Baicalein potentiated M1 macrophage polarization in cancer through targeting PI3Kγ/NF-κB signaling
S He, S Wang, S Liu, Z Li, X Liu, J Wu - Frontiers in pharmacology, 2021 - frontiersin.org
Baicalein is one of the bioactive compounds extracted from Scutellaria baicalensis. Recent
studies indicated the antitumor effects of baicalein, however, the underlying mechanisms are …
studies indicated the antitumor effects of baicalein, however, the underlying mechanisms are …
Ethnobotanical study of medicinal plants used by the indigenous community of the western region of Mizoram, India
Background Plants have long been utilized as traditional medicines by the inhabitants.
However, until recently, the traditional knowledge had not been extensively documented …
However, until recently, the traditional knowledge had not been extensively documented …
Serum myoglobin modulates kidney injury via inducing ferroptosis after exertional heatstroke
Y Luan, E Huang, J Huang, Z Yang, Z Zhou… - Journal of translational …, 2023 - degruyter.com
Abstract Background and Objectives Myoglobin released by rhabdomyolysis (RM) is
considered to be involved in pathogenesis of kidney disease caused by crush injury, but …
considered to be involved in pathogenesis of kidney disease caused by crush injury, but …
Baicalein suppresses NLRP3 and AIM2 inflammasome-mediated pyroptosis in macrophages infected by Mycobacterium tuberculosis via induced autophagy
B Ning, J Shen, F Liu, H Zhang, X Jiang - Microbiology Spectrum, 2023 - Am Soc Microbiol
Mycobacterium tuberculosis (Mtb) continues to pose a significant threat to global health
because it causes granulomas and systemic inflammatory responses during active …
because it causes granulomas and systemic inflammatory responses during active …
Nano-baicalein facilitates chemotherapy in breast cancer by targeting tumor microenvironment
F Zheng, Y Luo, Y Liu, Y Gao, W Chen, K Wei - International Journal of …, 2023 - Elsevier
Cancer-associated fibroblasts constitute a significant component in the tumor
microenvironment, playing a pivotal role in tumor proliferation, invasion, migration, and …
microenvironment, playing a pivotal role in tumor proliferation, invasion, migration, and …
Traditional herbal medicine discovery for the treatment and prevention of pulmonary arterial hypertension
Z Xue, Y Li, M Zhou, Z Liu, G Fan, X Wang… - Frontiers in …, 2021 - frontiersin.org
Pulmonary arterial hypertension (PAH) is characterized by pulmonary artery remodeling that
may subsequently culminate in right heart failure and premature death. Although there are …
may subsequently culminate in right heart failure and premature death. Although there are …
Synergistic combination of baicalein and rifampicin against Staphylococcus aureus biofilms
R Muniyasamy, I Manjubala - Frontiers in Microbiology, 2024 - frontiersin.org
Staphylococcus aureus, a Gram-positive bacterium, is a predominant pathogen associated
with various infections. The rapid emergence of antibiotic resistance has intensified the …
with various infections. The rapid emergence of antibiotic resistance has intensified the …
[HTML][HTML] Bioactive compounds from nature: Antioxidants targeting cellular transformation in response to epigenetic perturbations induced by oxidative stress
A Bouyahya, S Bakrim, S Aboulaghras… - Biomedicine & …, 2024 - Elsevier
Oxidative stress results from a persistent imbalance in oxidation levels that promotes
oxidants, playing a crucial role in the early and sustained phases of DNA damage and …
oxidants, playing a crucial role in the early and sustained phases of DNA damage and …