The four dengue virus (DENV) serotypes that circulate among humans emerged
independently from ancestral sylvatic progenitors that were present in non-human primates …

INTRODUCTION: Dengue is a vector-borne viral infection that endangers an estimated 2.5
billion people. Disease caused by dengue ranges from a relatively minor febrile illness to a …

This new edition has been produced to make widely available to health practitioners,
laboratory personnel, those involved in vector control and other public health officials, a …

The development of cell culture systems for virus propagation has led to major advances in
virus vaccine development. Primary and diploid cell culture systems are now being replaced …

Dengue viral infection has become an increasing global health concern with over two-fifths
of the world's population at risk of infection. It is the most rapidly spreading vector borne …

Dengue viruses (DENV) are the etiological agents of dengue fever (DF) and dengue
hemorrhagic fever (DHF). The DENV complex consists of four closely related viruses …

Dengue virus (DENV) infection is a worsening global health problem. The plaque reduction
neutralization test (PRNT) is currently considered to be the “gold standard” to characterize …

The spread of dengue virus throughout the tropics represents a major, rapidly growing
public health problem with an estimated 2· 5 billion people at risk of dengue fever and the …

After failed attempts at producing bacteria-based vaccines, the discovery of a viral agent
causing yellow fever and its isolation in monkeys opened new avenues of research …

Truncated recombinant dengue virus envelope protein subunits (80E) are efficiently
expressed using the Drosophila Schneider-2 (S2) cell expression system. Binding of …