The absence of cellular organelles in fiber cells and very high cytoplasmic protein
concentration (up to 900 mg/ml) minimize light scattering in the lens and ensure its …

Cataract is the leading cause of blindness worldwide and accounts for approximately half of
all forms of vision loss. Currently, the only way to treat cataracts is by surgery. However, with …

The eye lens consists of a layer of epithelial cells that overlay a series of differentiating fiber
cells that upon maturation lose their mitochondria, nuclei and other organelles. Lens …

PURPOSE: To provide a multidisciplinary synthesis of scientific information on disability,
discomfort, dazzling, and scotomatic (photostress) glare. DESIGN: Perspective. METHODS …

Cataracts cause vision loss and blindness by impairing the ability of the ocular lens to focus
light onto the retina. Various cataract risk factors have been identified, including drug …

αH-Crystallin, a high molecular weight form of α-crystallin, is one of the major proteins in the
lens nucleus. This high molecular weight aggregate (HMWA) plays an important role in the …

The “superpower” of invisibility is a reality and a necessity for many animals that live in
featureless environments like the open ocean, where there is nowhere to hide. How do …

The human ocular lens consists primarily of elongated, static fibers characterized by high
stability and low turnover, which differ dramatically in their composition and properties from …

The purpose is to determine the nature of the cellular rearrangements occurring through the
remodeling zone (RZ) in human donor lenses, identified previously by confocal microscopy …

Human nuclear cataract formation is a multi-factorial disease with contributions to light
scattering from many cellular sources that change their scattering properties over decades …