Non-canonical inflammasome pathway: The role of cell death and inflammation in Ehrlichiosis

AK Sharma, N Ismail - Cells, 2023 - mdpi.com
Activating inflammatory caspases and releasing pro-inflammatory mediators are two
essential functions of inflammasomes which are triggered in response to pathogen …

[HTML][HTML] Distribution of Rhipicephalus sanguineus and Heamaphysalis elliptica dog ticks and pathogens they are carrying: A systematic review

CL Van Wyk, S Mtshali, T Ramatla, KE Lekota… - … : Regional Studies and …, 2024 - Elsevier
The role of ixodid ticks especially Rhipicephalus sanguineus and Heamaphysalis elliptica in
the epidemiology of several diseases of veterinary and public health importance have been …

Detection of Anaplasma and Ehrlichia bacteria in humans, wildlife, and ticks in the Amazon rainforest

M Buysse, R Koual, F Binetruy, B de Thoisy… - Nature …, 2024 - nature.com
Tick-borne bacteria of the genera Ehrlichia and Anaplasma cause several emerging human
infectious diseases worldwide. In this study, we conduct an extensive survey for Ehrlichia …

Hepatocyte-specific regulation of autophagy and inflammasome activation via MyD88 during lethal Ehrlichia infection

O Teymournejad, AK Sharma, M Abdelwahed… - Frontiers in …, 2023 - frontiersin.org
Hepatocytes play a crucial role in host response to infection. Ehrlichia is an obligate
intracellular bacterium that causes potentially life-threatening human monocytic ehrlichiosis …

Expanding the universe of Piroplasmids: Morphological detection and phylogenetic positioning of putative novel piroplasmids in black-eared opossums (Didelphis …

ÁFX Oliveira, AC Calchi, AV Stocco, NV Stocco… - Parasitology …, 2023 - Springer
The growing proximity of wildlife to large urban niches arouses greater interest in
understanding wild reservoirs in the epidemiology of diseases of importance to animal and …

Type 1 secretion system and effectors in Rickettsiales

DC Bui, T Luo, JW McBride - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Obligate intracellular bacteria in the order Rickettsiales are transmitted by arthropod vectors
and cause life-threatening infections in humans and animals. While both type 1 and type 4 …

Efficacy and immune correlates of OMP-1B and virB2-4 vaccines for protection of dogs from tick transmission of ehrlichia chaffeensis

K Budachetri, M Lin, RC Chien, W Zhang, GN Brock… - Mbio, 2022 - Am Soc Microbiol
Ehrlichia chaffeensis, an obligatory intracellular bacterium, causes human monocytic
ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma …

[HTML][HTML] Emergence of ehrlichiosis by a new tick-borne Ehrlichia species in China

M Lu, XC Qin, YZ Jiang, Q Guo, XJ Jin, ZQ Teng… - International Journal of …, 2023 - Elsevier
Abstract Objectives From March to June 2021, the reported number of clinically diagnosed
endemic typhus in Anhui and Hubei provinces of China nearly increased four-fold compared …

[HTML][HTML] protective immunity and immunopathology of ehrlichiosis

N Ismail, A Sharma, L Soong… - Zoonoses (Burlington …, 2022 - ncbi.nlm.nih.gov
Human monocytic ehrlichiosis, a tick transmitted infection, ranges in severity from apparently
subclinical to a fatal toxic shock-like fatal disease. Models in immunocompetent mice range …

Ehrlichia effector TRP120 manipulates bacteremia to facilitate tick acquisition

T Zhang, RC Chien, K Budachetri, M Lin, P Boyaka… - Mbio, 2024 - Am Soc Microbiol
Ehrlichia species are obligatory intracellular bacteria that cause a potentially fatal disease,
human ehrlichiosis. The biomolecular mechanisms of tick acquisition of Ehrlichia and …