Measuring Absolute Coronary Flow and Microvascular Resistance by Thermodilution: JACC Review Topic of the Week

M Belmonte, E Gallinoro, NHJ Pijls… - Journal of the American …, 2024 - jacc.org
Diagnosing coronary microvascular dysfunction remains challenging, primarily due to the
lack of direct measurements of absolute coronary blood flow (Q) and microvascular …

Myocardial infarction with nonobstructive coronary arteries: from pathophysiology to therapeutic strategies

A Foà, L Canton, F Bodega… - Journal of …, 2023 - journals.lww.com
Myocardial infarction with nonobstructive coronary arteries (MINOCA) is a heterogeneous
group of clinical entities characterized by clinical evidence of acute myocardial infarction …

[HTML][HTML] Reproducibility of bolus versus continuous thermodilution for assessment of coronary microvascular function in patients with ANOCA

E Gallinoro, DT Bertolone… - …, 2023 - eurointervention.pcronline.com
Background: A bolus thermodilution-derived index of microcirculatory resistance (IMR) has
emerged as the standard for assessing coronary microvascular dysfunction (CMD) …

Multi-modality imaging in aortic stenosis: an EACVI clinical consensus document

MR Dweck, K Loganath, R Bing… - European Heart …, 2023 - academic.oup.com
In this EACVI clinical scientific update, we will explore the current use of multi-modality
imaging in the diagnosis, risk stratification, and follow-up of patients with aortic stenosis, with …

Coronary microvascular dysfunction in patients with heart failure: characterization of patterns in HFrEF versus HFpEF

P Paolisso, E Gallinoro, M Belmonte… - Circulation: Heart …, 2024 - Am Heart Assoc
BACKGROUND: Coronary microvascular dysfunction (CMD) is involved in heart failure (HF)
onset and progression, independently of HF phenotype and obstructive coronary artery …

Continuous vs bolus thermodilution to assess microvascular resistance reserve

E Gallinoro, DT Bertolone, T Mizukami… - Cardiovascular …, 2023 - jacc.org
Background Coronary flow reserve (CFR) and microvascular resistance reserve (MRR) can,
in principle, be derived by any method assessing coronary flow. Objectives The aim of this …

An interventional sheep model of severe aortic valve stenosis hemodynamics for the evaluation of alterations in coronary physiology and microvascular function

L Minten, T Langenaeken… - Journal of Applied …, 2024 - journals.physiology.org
We aimed to develop a large animal model of subcoronary aortic stenosis (AS) to study
intracoronary and microcirculatory hemodynamics. A total of three surgical techniques …

Outcomes in patients with moderate and asymptomatic severe aortic stenosis followed up in heart valve clinics

P Paolisso, M Beles, M Belmonte, E Gallinoro… - Heart, 2023 - heart.bmj.com
Background Heart valve clinics (HVC) have been introduced to manage patients with
valvular heart disease within a multidisciplinary team. Objective To determine the outcome …

Optimal measurement of coronary flow and microvascular function in animals and humans

L Minten, M Algoet, J Bennett, W Oosterlinck… - Circulation …, 2023 - Am Heart Assoc
Coronary microvascular dysfunction plays a major role in patients with cardiac ischemia
without flow limiting epicardial coronary stenosis, Takotsubo cardiomyopathy, aortic valve …

Myocardial sodium–glucose cotransporter 2 expression and cardiac remodelling in patients with severe aortic stenosis: The BIO‐AS study

L Scisciola, P Paolisso, M Belmonte… - European Journal of …, 2024 - Wiley Online Library
Aim Cardiac remodelling plays a major role in the prognosis of patients with aortic stenosis
(AS) and could impact the benefits of aortic valve replacement. Our study aimed to evaluate …