Cell invasion into the surrounding extracellular matrix or across tissue boundaries and
endothelial barriers occurs in both physiological and pathological scenarios such as …

The actin cytoskeleton and associated motor proteins provide the driving forces for
establishing the astonishing morphological diversity and dynamics of mammalian cells …

Importance Wiskott-Aldrich syndrome is a rare primary immunodeficiency associated with
severe microthrombocytopenia. Partially HLA antigen–matched allogeneic hematopoietic …

Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency with severe
platelet abnormalities and complex immunodeficiency. Although clinical gene therapy …

Wiskott‐Aldrich syndrome (WAS) is a rare X‐linked primary immunodeficiency characterized
by microthrombocytopenia, eczema, recurrent infections, and an increased incidence of …

The cellular functions of the actin cytoskeleton require precise regulation of both the
initiation of actin polymerization and the organization of the resulting filaments. The actin …

Actin filaments are major components of at least 15 distinct structures in metazoan cells.
These filaments assemble from a common pool of actin monomers, but do so at different …

Viral infection converts the normal functions of a cell to optimize viral replication and virion
production. One striking observation of this conversion is the reconfiguration and …

The Rho subgroup of the Rho GTPases consisting of RhoA, RhoB and RhoC induces a
specific type of actin cytoskeleton and carry out a variety of functions in the cell. mDia and …

A great hallmark of breast cancer is the absence or presence of estrogen receptors ERα and
ERβ, with a dominant role in cell proliferation, differentiation and cancer progression. Both …