[HTML][HTML] The Pivotal Role of Preclinical Animal Models in Anti-Cancer Drug Discovery and Personalized Cancer Therapy Strategies
H Guo, X Xu, J Zhang, Y Du, X Yang, Z He, L Zhao… - Pharmaceuticals, 2024 - mdpi.com
The establishment and utilization of preclinical animal models constitute a pivotal aspect
across all facets of cancer research, indispensably contributing to the comprehension of …
across all facets of cancer research, indispensably contributing to the comprehension of …
[HTML][HTML] Oral toxicity evaluation of cannabidiol
RG Henderson, TW Lefever, MM Heintz… - Food and Chemical …, 2023 - Elsevier
Use of cannabidiol (CBD) in humans has increased considerably in recent years. While
currently available studies suggest that CBD is relatively safe for human consumption, data …
currently available studies suggest that CBD is relatively safe for human consumption, data …
[HTML][HTML] Cannabidiol safety considerations: Development of a potential acceptable daily intake value and recommended upper intake limits for dietary supplement use
RG Henderson, M Vincent, BN Rivera… - Regulatory toxicology …, 2023 - Elsevier
Consumer use of hemp-derived products continues to rise, underscoring the need to
establish evidence-based safety guidance. The present study sought to develop …
establish evidence-based safety guidance. The present study sought to develop …
Toxicological mechanism of cannabidiol (CBD) exposure on zebrafish embryonic development
Y Wei, X Chen, Y Li, Y Guo, S Zhang, J Jin, J Li… - Food and Chemical …, 2024 - Elsevier
Cannabidiol (CBD) is the main component of plant Cannabis (Cannabis sativa), which
exhibits strong antioxidant and anti-inflammatory activities. With the legalization of CBD in …
exhibits strong antioxidant and anti-inflammatory activities. With the legalization of CBD in …
The Regulatory Challenges of Placing Dietary Ingredients on the European and US Market
MJ Tallon, DS Kalman - Journal of Dietary Supplements, 2024 - Taylor & Francis
The DSHEA is 30 years old and its place in providing legitimate protections for public health
through relevant agency oversight has created a patchwork of legal and scientific …
through relevant agency oversight has created a patchwork of legal and scientific …
[HTML][HTML] Subchronic oral toxicity assessment of a cannabis extract
MJ Tallon, R Child - Regulatory Toxicology and Pharmacology, 2023 - Elsevier
Cannabidiol (CBD) is present in Cannabis Sativa L. and has been used in medicines and
foods to deliver beneficial health effects. Despite this, research on CBD safety utilising …
foods to deliver beneficial health effects. Despite this, research on CBD safety utilising …
Assessment of the effects of cannabidiol and a CBD-rich hemp extract in Caenorhabditis elegans
JA Camacho, B Welch, M Ferguson, E Sepehr… - Frontiers in …, 2024 - frontiersin.org
Consumer use of cannabidiol (CBD) is growing, but there are still data gaps regarding its
possible adverse effects on reproduction and development. Multiple pathways and signaling …
possible adverse effects on reproduction and development. Multiple pathways and signaling …
[HTML][HTML] Genotoxicity evaluation of cannabidiol
RG Henderson, BT Welsh, KR Trexler… - Regulatory Toxicology …, 2023 - Elsevier
Consumer use of cannabidiol (CBD) for personal wellness purposes has garnered much
public interest. However, safety-related data on CBD in the public domain are limited …
public interest. However, safety-related data on CBD in the public domain are limited …
Cannabidiol for the treatment of alcohol use disorder: Examination of potential receptor mechanisms in a murine model of binge-like alcohol consumption
CJ Badolato - 2024 - ses.library.usyd.edu.au
Binge drinking is a risky pattern of alcohol intake and a major predictor of alcohol use
disorder (AUD). Current AUD medications have limited efficacy and poor patient …
disorder (AUD). Current AUD medications have limited efficacy and poor patient …