Physical properties of the bacterial outer membrane
J Sun, ST Rutherford, TJ Silhavy… - Nature Reviews …, 2022 - nature.com
It has long been appreciated that the Gram-negative outer membrane acts as a permeability
barrier, but recent studies have uncovered a more expansive and versatile role for the outer …
barrier, but recent studies have uncovered a more expansive and versatile role for the outer …
How to enter a bacterium: bacterial porins and the permeation of antibiotics
JD Prajapati, U Kleinekathöfer… - Chemical …, 2021 - ACS Publications
Despite tremendous successes in the field of antibiotic discovery seen in the previous
century, infectious diseases have remained a leading cause of death. More specifically …
century, infectious diseases have remained a leading cause of death. More specifically …
Lipopolysaccharide O-antigens—bacterial glycans made to measure
C Whitfield, DM Williams, SD Kelly - Journal of Biological Chemistry, 2020 - ASBMB
Lipopolysaccharides are critical components of bacterial outer membranes. The more
conserved lipid A part of the lipopolysaccharide molecule is a major element in the …
conserved lipid A part of the lipopolysaccharide molecule is a major element in the …
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …
[HTML][HTML] Lipopolysaccharides at solid and liquid interfaces: models for biophysical studies of the gram-negative bacterial outer membrane
Lipopolysaccharides (LPSs) are a constitutive element of the cell envelope of Gram-
negative bacteria, representing the main lipid in the external leaflet of their outer membrane …
negative bacteria, representing the main lipid in the external leaflet of their outer membrane …
The controversial role of LPS in platelet activation in vitro
Circulating platelets are responsible for hemostasis and thrombosis but are also primary
sensors of pathogens and are involved in innate immunity, inflammation, and sepsis. Sepsis …
sensors of pathogens and are involved in innate immunity, inflammation, and sepsis. Sepsis …
Outer Membrane Proteins and Efflux Pumps Mediated Multi-Drug Resistance in Salmonella: Rising Threat to Antimicrobial Therapy
Despite colossal achievements in antibiotic therapy in recent decades, drug-resistant
pathogens have remained a leading cause of death and economic loss globally. One such …
pathogens have remained a leading cause of death and economic loss globally. One such …
Restoring and enhancing the potency of existing antibiotics against drug-resistant gram-negative bacteria through the development of potent small-molecule …
The rapid and persistent emergence of drug-resistant bacteria poses a looming public
health crisis. The possible task of developing new sets of antibiotics to replenish the existing …
health crisis. The possible task of developing new sets of antibiotics to replenish the existing …
MALDI‐TOF mass spectroscopy applications in clinical microbiology
There is a range of proteomics methods to spot and analyze bacterial protein contents such
as liquid chromatography‐mass spectrometry (LC‐MS), two‐dimensional gel …
as liquid chromatography‐mass spectrometry (LC‐MS), two‐dimensional gel …
Genomic Diversity, Antimicrobial Resistance, and Virulence Gene Profiles of Salmonella Serovar Kentucky Isolated from Humans, Food, and Animal Ceca Content …
Salmonella serovar Kentucky is frequently isolated from chickens and dairy cattle, but
recovery from humans is comparatively low based on the US National Antimicrobial …
recovery from humans is comparatively low based on the US National Antimicrobial …