The analysis of the dynamic behaviour of genome-scale models of metabolism (GEMs)
currently presents considerable challenges because of the difficulties of simulating such …

Background The kinetic modeling of biological systems is mainly composed of three steps
that proceed iteratively: model building, simulation and analysis. In the first step, it is usually …

Petri nets have become a tremendously important mathematical and graphical tool in
modeling and performance evaluation of real systems with discrete events that are …

The bio-cell cycle is controlled by a complex biochemical network of signaling pathways.
Modeling such challenging networks accurately is imperative for the understanding of their …

The characterization of biological systems with respect to their behavior and functionality
based on versatile biochemical interactions is a major challenge. To understand these …

En la mayoría de los casos en los que se requiere describir una red biológica se propone
un sistema de ecuaciones diferenciales acopladas, que luego se resuelve por métodos …

Over the past years, an increasing amount of biological data produced shows the impor
tance of data repositories. The databases ensure an easier way to reuse and share research …

RESUMO O Brasil é um dos líderes mundiais na produção de etanol, sendo pioneiro no
ramo do álcool combustível. No entanto, o país já enfrenta uma grande limitação imposta …

Kurzdarstellung Die Charakterisierung von Verhaltens-und Funktionsweisen biologischer
Systeme stellt aufgrund vielfältiger biochemischer Interaktionen eine große …

Kinetic modeling of biological systems is a fundamental element of systems biology as a tool
for performing experiments in silico with biotechnological and biomedical applications. It is …