Epidermolysis bullosa (EB) is a clinically and genetically heterogeneous group of inherited
blistering diseases that affects~ 500,000 people worldwide. Clinically, individuals with EB …

Purpose To conduct a systematic review on outcomes of three different techniques of
autologous limbal stem cell transplantation (LSCT): conjunctival-limbal autografting (CLAu) …

Herlitz junctional epidermolysis bullosa (H-JEB) is an incurable, devastating, and mostly
fatal inherited skin disease for which there is only supportive care. H-JEB is caused by loss …

Corneal pathologies are a major cause of blindness and visual impairment, especially in the
developing world. However, not only is there a global shortage of donor corneal tissue, but a …

Recessive dystrophic epidermolysis bullosa (RDEB) and junctional epidermolysis bullosa
(JEB) are lethal blistering skin disorders resulting from mutations in genes coding for type VII …

RNA trans-splicing has become a versatile tool in the gene therapy of monogenetic
diseases. This technique is especially valuable for the correction of mutations in large genes …

For most disorders caused by mutations in genes encoding basement membrane (BM)
proteins, there are at present only limited treatment options available. Genetic BM-linked …

Severe generalized junctional epidermolysis bullosa (JEB), a lethal genodermatosis, is
mainly caused by premature termination codons (PTCs) in one of the three genes encoding …

Epidermolysis Bullosa (EB) is a group of rare genetic disorders that compromise the
structural integrity of the skin such that blisters and subsequent erosions occur after minor …

Recessive dystrophic epidermolysis bullosa (RDEB) is caused by defects in type-VII
collagen (C7), a protein encoded by the COL7A1 gene and essential for anchoring fibril …