Transcription factors play an indispensable role in maintaining cellular viability and finely
regulating complex internal metabolic networks. These crucial bioactive functions rely on …

As a promising industrial microorganism, methylotroph is capable of using methane or
methanol as the sole carbon source natively, which has been utilized in the biosynthesis of …

Serratia marcescens, a Gram-negative bacterium, is one of the known disease-causing
pathogens. It is resistant to ampicillin, macrolides, cephalosporins, cefotaxime, and …

Host-microbe interactions are virtually bidirectional, but how the host affects their
microbiome is poorly understood. Here, we report that the host is a critical modulator to …

NorR, as a single-target regulator, has been demonstrated to be involved in NO
detoxification in bacteria under anaerobic conditions. Here, the norR gene was identified …

BarA/UvrY, a two-component system and global regulator that controls expression of more
than a hundred of genes involved in virulence, motility, biofilm formation, and central carbon …

(−)-α-Bisabolol exhibits analgesic, anti-inflammatory, and skin-soothing properties and is
widely applied in the cosmetic and pharmaceutical industries. The use of plant essential oil …

Tolerance to acid stress is a crucial property of probiotics against gastric acids. The
malolactic enzyme pathway is one of the most important acid resistance systems in lactic …

Simple Summary With the advancement of synthetic biology and metabolic engineering,
regulatory elements applied for the accurate expression of target genes have become more …

Acidithiobacillus caldus is a typical extreme acidophile widely used in the
biohydrometallurgical industry, which often experiences extreme environmental stress in its …