Identification of drug–target interactions is an important process in drug discovery. Although
high-throughput screening and other biological assays are becoming available …

Tumor genome sequencing leads to documenting thousands of DNA mutations and other
genomic alterations. At present, these data cannot be analyzed adequately to aid in the …

Accumulating experimental studies have demonstrated important associations between
alterations and dysregulations of lncRNAs and the development and progression of various …

In recent years, accumulating evidences have shown that the dysregulations of lncRNAs are
associated with a wide range of human diseases. It is necessary and feasible to analyze …

Natural products with polypharmacological profiles have demonstrated promise as novel
therapeutics for various complex diseases, including cancer. Currently, many gaps exist in …

Cumulative verified experimental studies have demonstrated that microRNAs (miRNAs)
could be closely related with the development and progression of human complex diseases …

Drug–target interaction (DTI) prediction plays an important role in drug repositioning, drug
discovery and drug design. However, due to the large size of the chemical and genomic …

Diverse forms of resistance to anticancer drugs can lead to the failure of chemotherapy.
Drug resistance is one of the most intractable issues for successfully treating cancer in …

Importance Decisions regarding adjuvant therapy in patients with stage II colorectal cancer
(CRC) have been among the most challenging and controversial in oncology over the past …

An increasing number of evidences indicate microbes are implicated in human physiological
mechanisms, including complicated disease pathology. Some microbes have been …