Microtia is a congenital anomaly of the ear that ranges in severity from mild structural
abnormalities to complete absence of the ear, and can occur as an isolated birth defect or as …

The mammalian ear is a complex structure divided into three main parts: the outer; middle;
and inner ear. These parts are formed from all three germ layers and neural crest cells …

The Hox genes are an evolutionarily conserved family of genes, which encode a class of
important transcription factors that function in numerous developmental processes …

Microtia is a congenital anomaly, characterised by a small, abnormally shaped auricle
(pinna). It is usually accompanied by a narrow, blocked or absent ear canal. Microtia can …

Microtia is a term used to describe a wide array of phenotypic presentations of the outer ear.
Although the majority of the cases are isolated in nature, much of our understanding of the …

External ear abnormalities are frequent in newborns ranging from microtia to partial auricle
duplication. Little is known about the molecular mechanisms orchestrating external ear …

Congenital hearing disorders affect millions of children worldwide and can significantly
impact acquisition of speech and language. Efforts to identify the developmental genetic …

The cochleovestibular (CV) nerve, which connects the inner ear to the brain, is the nerve that
enables the senses of hearing and balance. The aim of this study was to document the …

Dental follicle (DF) can develop into periodontal tissues including periodontal ligament,
cementum, and alveolar bone. Possessing superior pluripotency and osteogenic capacity …

Microtia is a genetic condition affecting the external ears and presents clinically along a
wide spectrum: minimally affected ears are small with minor shape abnormalities; extremely …