Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria
CW Hall, TF Mah - FEMS microbiology reviews, 2017 - academic.oup.com
Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …
Clinical significance and pathogenesis of staphylococcal small colony variants in persistent infections
BC Kahl, K Becker, B Löffler - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Small colony variants (SCVs) were first described more than 100 years ago for
Staphylococcus aureus and various coagulase-negative staphylococci. Two decades ago …
Staphylococcus aureus and various coagulase-negative staphylococci. Two decades ago …
Bacterial stress responses as determinants of antimicrobial resistance
K Poole - Journal of Antimicrobial Chemotherapy, 2012 - academic.oup.com
Bacteria encounter a myriad of stresses in their natural environments, including, for
pathogens, their hosts. These stresses elicit a variety of specific and highly regulated …
pathogens, their hosts. These stresses elicit a variety of specific and highly regulated …
Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection
L Tuchscherr, E Medina, M Hussain… - EMBO molecular …, 2011 - embopress.org
Staphylococcus aureus is a frequent cause for serious, chronic and therapy‐refractive
infections in spite of susceptibility to antibiotics in vitro. In chronic infections, altered bacterial …
infections in spite of susceptibility to antibiotics in vitro. In chronic infections, altered bacterial …
Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections
L Tuchscherr, M Bischoff, SM Lattar… - PLoS …, 2015 - journals.plos.org
Staphylococcus aureus is a major human pathogen that causes a range of infections from
acute invasive to chronic and difficult-to-treat. Infection strategies associated with persisting …
acute invasive to chronic and difficult-to-treat. Infection strategies associated with persisting …
Persistence of Staphylococcus aureus: Multiple Metabolic Pathways Impact the Expression of Virulence Factors in Small-Colony Variants (SCVs)
L Tuchscherr, B Löffler, RA Proctor - Frontiers in Microbiology, 2020 - frontiersin.org
Staphylococcus aureus is able to survive within host cells by switching its phenotype to the
small-colony variant (SCV) phenotype. The emergence of SCVs is associated with the …
small-colony variant (SCV) phenotype. The emergence of SCVs is associated with the …
Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data
LG Garcia, S Lemaire, BC Kahl, K Becker… - Journal of …, 2013 - academic.oup.com
The pathogen Staphylococcus aureus uses various strategies for persisting in the host,
among which switching to a small-colony variant (SCV) phenotype is of particular biological …
among which switching to a small-colony variant (SCV) phenotype is of particular biological …
Staphylococcus aureus persistence properties associated with bovine mastitis and alternative therapeutic modalities
Staphylococcus aureus is an important agent of contagious bovine intramammary infections
in dairy cattle. Its ability to persist inside the udder is based on the presence of important …
in dairy cattle. Its ability to persist inside the udder is based on the presence of important …
Staphylococcus aureus Adapts to Oxidative Stress by Producing H2O2-Resistant Small-Colony Variants via the SOS Response
KL Painter, E Strange, J Parkhill, KB Bamford… - Infection and …, 2015 - Am Soc Microbiol
The development of chronic and recurrent Staphylococcus aureus infections is associated
with the emergence of slow-growing mutants known as small-colony variants (SCVs), which …
with the emergence of slow-growing mutants known as small-colony variants (SCVs), which …
Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2 …
G Mitchell, DL Séguin, AE Asselin, E Déziel… - BMC microbiology, 2010 - Springer
Abstract Background Staphylococcus aureus and Pseudomonas aeruginosa are often found
together in the airways of cystic fibrosis (CF) patients. It was previously shown that the P …
together in the airways of cystic fibrosis (CF) patients. It was previously shown that the P …