Diversity, mechanisms, and significance of macrophage plasticity

M Locati, G Curtale, A Mantovani - Annual Review of Pathology …, 2020 - annualreviews.org
Macrophages are a diverse set of cells present in all body compartments. This diversity is
imprinted by their ontogenetic origin (embryonal versus adult bone marrow–derived cells); …

Interleukin-18 in inflammatory kidney disease

Y Hirooka, Y Nozaki - Frontiers in medicine, 2021 - frontiersin.org
Interleukin (IL)-18, a member of the IL-1 superfamily, is a pro-inflammatory cytokine that is
structurally similar to IL-1β. IL-18 promotes the production of interferon gamma (IFN-γ) and …

Differences in inflammatory cytokine profile in obesity-associated asthma: effects of weight loss

M Bantulà, V Tubita, J Roca-Ferrer, J Mullol… - Journal of Clinical …, 2022 - mdpi.com
Obesity and asthma are associated with systemic inflammation maintained by mediators
released by adipose tissue and lung. This study investigated the inflammatory serum …

Interleukin-1 receptor accessory protein (IL-1RAP): A magic bullet candidate for immunotherapy of human malignancies

AZ Mehrabadi, F Shahba, H Khorramdelazad… - Critical Reviews in …, 2024 - Elsevier
IL-1, plays a role in some pathological inflammatory conditions. This pro-inflammatory
cytokine also has a crucial role in tumorigenesis and immune responses in the tumor …

New insights into molecular mechanisms of chronic kidney disease

W Frąk, J Kućmierz, M Szlagor, E Młynarska, J Rysz… - Biomedicines, 2022 - mdpi.com
Chronic kidney disease (CKD) is a major public health problem with a developing incidence
and prevalence. As a consequence of the growing number of patients diagnosed with renal …

Effects of Elephantopus scaber extract on growth, proximate composition, immunity, intestinal microbiota and resistance of the GIFT strain of Nile tilapia Oreochromis …

JR Xu, PH Zheng, XX Zhang, JT Li, HQ Chen… - Fish & Shellfish …, 2022 - Elsevier
This study aimed to investigate the effects of Elephantopus scaber extract on the GIFT
(genetic improvement of farmed tilapia) strain of Nile tilapia Oreochromis niloticus. A total of …

The role of IL-38 in intestinal diseases-its potential as a therapeutic target

Q Wang, L Ma, C An, SG Wise, S Bao - Frontiers in Immunology, 2022 - frontiersin.org
IL-38, an anti-inflammatory cytokine, is a key regulator of homeostasis in host immunity.
Intestinal immunity plays a critical role in defence against pathogenic invasion, as it is the …

Anti-inflammatory effects of lavender and eucalyptus essential oils on the in vitro cell culture model of bladder pain syndrome using T24 cells

A Horváth, E Pandur, K Sipos, G Micalizzi… - … Medicine and Therapies, 2022 - Springer
Background Interstitial cystitis (IC) has a chronic chemical irritation and inflammation of non-
bacterial origin in the bladder wall leading to various severe symptoms. There is evidence …

[HTML][HTML] COVID-19 stokes inflammasomes

C Bryant - Journal of Experimental Medicine, 2021 - rupress.org
The poor success rate of treating patients with aggressive sepsis in SARS-CoV-2 infections
has highlighted again the challenges of managing systemic inflammatory conditions. In this …

Inhibition of Cyclin-Dependent Kinases 8/19 Restricts Bacterial and Virus-Induced Inflammatory Responses in Monocytes

EK Kokinos, SA Tsymbal, AV Galochkina… - Viruses, 2023 - mdpi.com
Hyperactivation of the immune system remains a dramatic, life-threatening complication of
viral and bacterial infections, particularly during pneumonia. Therapeutic approaches to …