A Review of Dual‐Task Walking Deficits in People with Parkinson′ s Disease: Motor and Cognitive Contributions, Mechanisms, and Clinical Implications

VE Kelly, AJ Eusterbrock… - Parkinson's …, 2012 - Wiley Online Library
Gait impairments in Parkinson′ s disease (PD) are exacerbated under dual‐task conditions
requiring the simultaneous performance of cognitive or motor tasks. Dual‐task walking …

Do we always prioritize balance when walking? Towards an integrated model of task prioritization

G Yogev‐Seligmann, JM Hausdorff… - Movement …, 2012 - Wiley Online Library
Previous studies suggest that strategies such as “posture first” are implicitly employed to
regulate safety when healthy adults walk while simultaneously performing another task …

Gait analysis with wearables predicts conversion to parkinson disease

S Del Din, M Elshehabi, B Galna, MA Hobert… - Annals of …, 2019 - Wiley Online Library
Objective Quantification of gait with wearable technology is promising; recent cross‐
sectional studies showed that gait characteristics are potential prodromal markers for …

IMU-based classification of Parkinson's disease from gait: A sensitivity analysis on sensor location and feature selection

C Caramia, D Torricelli, M Schmid… - IEEE journal of …, 2018 - ieeexplore.ieee.org
Inertial measurement units (IMUs) have a long-lasting popularity in a variety of industrial
applications from navigation systems to guidance and robotics. Their use in clinical practice …

Progression of gait dysfunction in incident Parkinson's disease: impact of medication and phenotype

B Galna, S Lord, DJ Burn, L Rochester - Movement Disorders, 2015 - Wiley Online Library
Gait impairment in Parkinson's disease (PD) persists despite the use of dopaminergic
therapy. Motor phenotype associated with greater postural instability and gait difficulty is …

A clinical view on the development of technology‐based tools in managing Parkinson's disease

W Maetzler, J Klucken, M Horne - Movement Disorders, 2016 - Wiley Online Library
Recently, quantitative, objective, and easy‐to‐use technology‐based tools that can assess
PD features over long time periods have been developed and generate clinically relevant …

Objective biomarkers of balance and gait for Parkinson's disease using body‐worn sensors

FB Horak, M Mancini - Movement Disorders, 2013 - Wiley Online Library
Balance and gait impairments characterize the progression of Parkinson's disease (PD),
predict the risk of falling, and are important contributors to reduced quality of life. Advances …

The nature of dual-task interference during gait in incident Parkinson's disease

L Rochester, B Galna, S Lord, D Burn - Neuroscience, 2014 - Elsevier
Dual-task interference during gait is a common phenomenon in older adults and people with
Parkinson's disease (PD). Dual-task performance is driven by cognitive processes involving …

Cholinergic dysfunction contributes to gait disturbance in early Parkinson's disease

L Rochester, AJ Yarnall, MR Baker, RV David, S Lord… - Brain, 2012 - academic.oup.com
Gait disturbance is an early feature in Parkinson's disease. Its pathophysiology is poorly
understood; however, cholinergic dysfunction may be a non-dopaminergic contributor to …

A validated smartphone-based assessment of gait and gait variability in Parkinson's disease

RJ Ellis, YS Ng, S Zhu, DM Tan, B Anderson… - PLoS one, 2015 - journals.plos.org
Background A well-established connection exists between increased gait variability and
greater fall likelihood in Parkinson's disease (PD); however, a portable, validated means of …