Computational tools for modern vaccine development

Sunita, A Sajid, Y Singh, P Shukla - Human vaccines & …, 2020 - Taylor & Francis
Vaccines play an essential role in controlling the rates of fatality and morbidity. Vaccines not
only arrest the beginning of different diseases but also assign a gateway for its elimination …

Plasmodium vivax vaccine: What is the best way to go?

GTS Veiga, MR Moriggi, JF Vettorazzi… - Frontiers in …, 2023 - frontiersin.org
Malaria is one of the most devastating human infectious diseases caused by Plasmodium
spp. parasites. A search for an effective and safe vaccine is the main challenge for its …

In silico designing of a multi-epitope vaccine against Burkholderia pseudomallei: Reverse vaccinology and immunoinformatics

M Shahab, C Hayat, R Sikandar, G Zheng… - Journal of Genetic …, 2022 - Elsevier
Background Burkholderia pseudomallei is an infectious agent causing severe disease
melioidosis resulting in pneumonia, fever, and acute septicemia in humans. B. pseudomallei …

A cost-effectiveness tool for informing policies on Zika virus control

JA Alfaro-Murillo, AS Parpia… - PLoS neglected …, 2016 - journals.plos.org
Background As Zika virus continues to spread, decisions regarding resource allocations to
control the outbreak underscore the need for a tool to weigh policies according to their cost …

Natural acquisition of immunity to Plasmodium vivax: epidemiological observations and potential targets

I Mueller, MR Galinski, T Tsuboi… - Advances in …, 2013 - Elsevier
Population studies show that individuals acquire immunity to Plasmodium vivax more
quickly than Plasmodium falciparum irrespective of overall transmission intensity, resulting …

What Is Known about the Immune Response Induced by Plasmodium vivax Malaria Vaccine Candidates?

C López, Y Yepes-Pérez, N Hincapié-Escobar… - Frontiers in …, 2017 - frontiersin.org
Malaria caused by Plasmodium vivax continues being one of the most important infectious
diseases around the world; P. vivax is the second most prevalent species and has the …

mRNA-based vaccine designing against Epstein-Barr virus to induce an immune response using immunoinformatic and molecular modelling approaches

HN Althurwi, KM Alharthy, FF Albaqami… - International Journal of …, 2022 - mdpi.com
Epstein-Barr Virus (EBV) is a human pathogen that has a morbidity rate of 90% in adults
worldwide. Infectious mononucleosis is caused by EBV replication in B cells and epithelial …

Insights into the naturally acquired immune response to Plasmodium vivax malaria

RJ Longley, J Sattabongkot, IVO Mueller - Parasitology, 2016 - cambridge.org
Plasmodium vivax is the most geographically widespread of the malaria parasites causing
human disease, yet it is comparatively understudied compared with Plasmodium falciparum …

[HTML][HTML] Alterations in cytokines and haematological parameters during the acute and convalescent phases of Plasmodium falciparum and Plasmodium vivax …

RN Rodrigues-da-Silva, JC Lima-Junior… - Memórias do Instituto …, 2014 - SciELO Brasil
Haematological and cytokine alterations in malaria are a broad and controversial subject in
the literature. However, few studies have simultaneously evaluated various cytokines in a …

Immunodominant and neutralizing linear B-cell epitopes spanning the spike and membrane proteins of porcine epidemic diarrhea virus

K Polyiam, M Ruengjitchatchawalya… - Frontiers in …, 2022 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) is the causative agent of PED, an enteric disease
that causes high mortality rates in piglets. PEDV is an alphacoronavirus that has high …