The microbial biosynthesis of noncanonical terpenoids

M Ma, M Li, Z Wu, X Liang, Q Zheng, D Li… - Applied Microbiology …, 2024 - Springer
Terpenoids are a class of structurally complex, naturally occurring compounds found
predominantly in plant, animal, and microorganism secondary metabolites. Classical …

Bioelectric Pharmacology of Cancer: A Systematic Review of Ion Channel Drugs Affecting the Cancer Phenotype

K Kofman, M Levin - Progress in Biophysics and Molecular Biology, 2024 - Elsevier
Cancer is a pernicious and pressing medical problem; moreover, it is a failure of
multicellular morphogenesis that sheds much light on evolutionary developmental biology …

Nanoformulated herbal compounds: enhanced antibacterial efficacy of camphor and thymol-loaded nanogels

A Abdollahi, N Fereydouni, H Moradi… - … Medicine and Therapies, 2024 - Springer
Herbal components are highly useful assets for the advancement of novel antibacterial
drugs. Nanotechnology holds great promise as an approach to enhance the effectiveness …

Chemical Composition and Biological Activity of Salvia officinalis L. Essential Oil

Z Jažo, M Glumac, V Paštar, S Bektić, M Radan, I Carev - Plants, 2023 - mdpi.com
In our study, we investigated the chemical composition and cytotoxic activity of essential oils
isolated from Dalmatian sage (Salvia officinalis L.) collected along the Adriatic coast of …

Menthol: An underestimated anticancer agent

Y Zhao, H Pan, W Liu, E Liu, Y Pang, H Gao… - Frontiers in …, 2023 - frontiersin.org
Menthol, a widely used natural, active compound, has recently been shown to have
anticancer activity. Moreover, it has been found to have a promising future in the treatment of …

Nanoparticle‐Based Drug Delivery Platform for Simultaneous Administration of Phytochemicals and Chemotherapeutics: Emerging Trends in Cancer Management

SM Kawish, S Sharma, P Gupta… - Particle & Particle …, 2024 - Wiley Online Library
Despite progress in cancer treatments, it remains a leading cause of death worldwide.
Current chemotherapy is often hampered by side effects, tissue damage, and drug …

Exploring the Pharmacological Potential of the Chemically Characterized Essential Oil from Clinopodium nepeta Subsp. Ascendens: A Combined In Vitro and In Silico …

M Taibi, EH Loukili, A Elbouzidi, A Baraich… - Moroccan Journal of …, 2024 - revues.imist.ma
This thorough examination explores the various biological characteristics present in the
essential oil derived from Clinopodium nepeta subsp. ascendens (CNEO), a subspecies …

Comparative Cytotoxicity of Menthol and Eucalyptol: An In Vitro Study on Human Gingival Fibroblasts

C Puig-Herreros, JL Sanz, D García-Bernal… - Pharmaceutics, 2024 - mdpi.com
The aim of this study was to assess the influence of eucalyptol and menthol on the cell
viability, migration, and reactive oxygen species production of human gingival fibroblasts …

Preformulation Studies of Novel Menthol Prodrugs with Antiparasitic Activity: Chemical Stability, In Silico, and In Vitro Permeability Assays

CM Clemente, R Onnainty, N Usseglio… - Drugs and Drug …, 2023 - mdpi.com
Based on the demonstrated and reported trypanocidal, leishmanicidal, and antiplasmodial
activities of two menthol prodrugs, it was decided to proceed with preformulation studies …

Potential natural hydrosol blend TGLON suppresses the proliferation of five cancer cell lines and also ameliorates idiopathic pulmonary fibrosis in mouse model

WH Huang, ML Chang, CC Lin, CP Wang, FJ Tsai… - 2024 - researchsquare.com
Background: Previous studies on natural substances for tumor cell inhibition have
predominantly concentrated on efficacy, often overlooking safety concerns. This research …