Role of CD14 in human disease

D Sharygin, LG Koniaris, C Wells, TA Zimmers… - …, 2023 - Wiley Online Library
The cell surface antigen CD14 is primarily understood to act as a co‐receptor for toll‐like
receptors (TLRs) to activate innate immunity responses to pathogens and tissue injury in …

Molecular signatures in hepatocellular carcinoma: A step toward rationally designed cancer therapy

DJ Erstad, BC Fuchs, KK Tanabe - Cancer, 2018 - Wiley Online Library
Molecular characterization of hepatocellular carcinoma (HCC) has greatly improved our
understanding of disease pathogenesis. Mutational analysis, RNA and microRNA …

HCMDB: the human cancer metastasis database

G Zheng, Y Ma, Y Zou, A Yin, W Li… - Nucleic acids …, 2018 - academic.oup.com
Metastasis is the main event leading to death in cancer patients. Over the past decade, high-
throughput technologies have provided genome-wide view of transcriptomic changes …

Ubiquitin-like modifier activating enzyme 1 as a novel diagnostic and prognostic indicator that correlates with ferroptosis and the malignant phenotypes of liver cancer …

Y Shan, G Yang, H Huang, Y Zhou, X Hu, Q Lu… - Frontiers in …, 2020 - frontiersin.org
Purpose Ferroptosis is a type of cell death that is iron dependent, a characteristic that
distinguishes it from necrosis, apoptosis, and autophagy. However, the ferroptotic …

NT5DC2 promotes tumor cell proliferation by stabilizing EGFR in hepatocellular carcinoma

KS Li, XD Zhu, HD Liu, SZ Zhang, XL Li, N Xiao… - Cell Death & …, 2020 - nature.com
Most hepatocellular carcinoma (HCC) patients are diagnosed at an advanced stage;
however, the effect of systemic therapy on advanced HCC remains undetermined …

Classification and prognosis prediction from histopathological images of hepatocellular carcinoma by a fully automated pipeline based on machine learning

H Liao, T Xiong, J Peng, L Xu, M Liao, Z Zhang… - Annals of surgical …, 2020 - Springer
Objective The aim of this study was to develop quantitative feature-based models from
histopathological images to distinguish hepatocellular carcinoma (HCC) from adjacent …

Development of an autophagy-based and stemness-correlated prognostic model for hepatocellular carcinoma using bulk and single-cell RNA-sequencing

S Shen, R Wang, H Qiu, C Li, J Wang, J Xue… - Frontiers in Cell and …, 2021 - frontiersin.org
Accumulating evidence has proved that autophagy serves as a tumor promoter in formed
malignancies, and the autophagy-related prognostic signatures have been constructed as …

[HTML][HTML] A new risk score based on twelve hepatocellular carcinoma-specific gene expression can predict the patients' prognosis

T Lin, J Gu, K Qu, X Zhang, X Ma, R Miao… - Aging (albany …, 2018 - ncbi.nlm.nih.gov
A large panel of molecular biomarkers have been identified to predict the prognosis of
hepatocellular carcinoma (HCC), yet with limited clinical application due to difficult …

Klotho‐beta and fibroblast growth factor 19 expression correlates with early recurrence of resectable hepatocellular carcinoma

ZZ Lin, C Hsu, YM Jeng, FC Hu, HW Pan… - Liver …, 2019 - Wiley Online Library
Abstract Background and Aims Fibroblast growth factor 19 (FGF19) and fibroblast growth
factor receptor 4 (FGFR4) signalling play critical roles in hepatocarcinogenesis. This study …

[HTML][HTML] Centrosomal protein 290 is a novel prognostic indicator that modulates liver cancer cell ferroptosis via the Nrf2 pathway

Y Shan, G Yang, Q Lu, X Hu, D Qi, Y Zhou… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Ferroptosis is an iron-dependent form of cell death. In spite of its significance in
pathogenesis and disease progression, ferroptotic signal transduction in HBV-HCC has not …