[HTML][HTML] Effects of endocannabinoid system modulation on cognitive and emotional behavior

C Zanettini, LV Panlilio, M Aliczki… - Frontiers in behavioral …, 2011 - frontiersin.org
Cannabis has long been known to produce cognitive and emotional effects. Research has
shown that cannabinoid drugs produce these effects by driving the brain's endogenous …

The effect of cannabis use on memory function: an update

T Schoeler, S Bhattacharyya - Substance abuse and rehabilitation, 2013 - Taylor & Francis
Investigating the effects of cannabis use on memory function appears challenging. While
early observational investigations aimed to elucidate the longer-term effects of cannabis use …

A behavioural comparison of acute and chronic Δ9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice

LE Long, R Chesworth, XF Huang… - International Journal …, 2010 - academic.oup.com
Cannabis contains over 70 unique compounds and its abuse is linked to an increased risk of
developing schizophrenia. The behavioural profiles of the psychotropic cannabis constituent …

Paracetamol (acetaminophen) administration during neonatal brain development affects cognitive function and alters its analgesic and anxiolytic response in adult …

H Viberg, P Eriksson, T Gordh… - Toxicological …, 2014 - academic.oup.com
Paracetamol (acetaminophen) is one of the most commonly used drugs for the treatment of
pain and fever in children, both at home and in the clinic, and is now also found in the …

Cholecystokinin-expressing interneurons of the medial prefrontal cortex mediate working memory retrieval

R Nguyen, S Venkatesan, M Binko… - Journal of …, 2020 - Soc Neuroscience
Distinct components of working memory are coordinated by different classes of inhibitory
interneurons in the PFC, but the role of cholecystokinin (CCK)-positive interneurons remains …

A weak El Niño/Southern Oscillation with delayed seasonal growth around 4,300 years ago

HV McGregor, MJ Fischer, MK Gagan, D Fink… - Nature …, 2013 - nature.com
Earth's interannual climate variability is dominated by El Niño/Southern Oscillation (ENSO).
Palaeoclimate records indicate a lower ENSO variance during the middle Holocene …

Behavioral methods to study learning and memory in rats

JA Quillfeldt - Rodent model as tools in ethical biomedical research, 2016 - Springer
This century-old observation is still valid today, despite everything we have learned about
the mammal nervous system, especially in the area of neurobiology of learning and memory …

[HTML][HTML] Hippocampal CB1 receptors mediate the memory impairing effects of Δ9-tetrahydrocannabinol

LE Wise, AJ Thorpe, AH Lichtman - Neuropsychopharmacology, 2009 - nature.com
It is firmly established that the hippocampus, a brain region implicated in spatial learning,
episodic memory, and consolidation, contains a high concentration of CB 1 receptors …

Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids

E Puighermanal, A Busquets-Garcia… - … of the Royal …, 2012 - royalsocietypublishing.org
Exogenous cannabinoids, such as delta9-tetrahydrocannabinol (THC), as well as the
modulation of endogenous cannabinoids, affect cognitive function through the activation of …

Δ-9-Tetrahydrocannabinol and Cannabidiol produce dissociable effects on prefrontal cortical executive function and regulation of affective behaviors

HJ Szkudlarek, SJ Desai, J Renard, B Pereira… - …, 2019 - nature.com
The use of cannabis for therapeutic and recreational purposes is growing exponentially.
Nevertheless, substantial questions remain concerning the potential cognitive and affective …